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. 2023 Feb 19;12(2):350.
doi: 10.3390/pathogens12020350.

Prevalence of HPV and Assessing Type-Specific HPV Testing in Cervical High-Grade Squamous Intraepithelial Lesions in Poland

Marcin Przybylski  1   2 , Dominik Pruski  2   3 , Katarzyna Wszołek  4 , Mateusz de Mezer  5 , Jakub Żurawski  5 , Robert Jach  6 , Sonja Millert-Kalińska  2   7
Affiliations

Prevalence of HPV and Assessing Type-Specific HPV Testing in Cervical High-Grade Squamous Intraepithelial Lesions in Poland

Marcin Przybylski et al. Pathogens. .

Abstract

The prevalence and distribution of oncogenic human papillomavirus (HPV) genotypes in women who underwent screening for cervical cancer in the Wielkopolska region, Poland, were assessed, and the correlation of genotypes with the histological results was evaluated. Cervical samples were collected from 2969 women for cervical cancer screening. Participants were screened by liquid-based cytology and HPV genotyping (n = 1654) and referred to colposcopy and punch biopsy (n = 616) if recommended. HPV genotypes 16, 31, 52, 66, 53, and 51 are the most frequent types in the studied population. Genotypes 16 and 31 account for nearly one-fifth of the infections of diagnosed HPV infections. HPV 16, 31, and 52 are found in nearly 80% of premalignant HSIL lesions (CIN 2 and CIN 3). That leads to the conclusion that vaccination programs should cover as many types of HPV as possible and shows the urgent need to vaccinate the Polish population with a 9-valent vaccine.

Keywords: HPV testing; HSIL; epidemiology.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
LBC—liquid-based cytology; HPV—human papillomavirus; LSIL—low-grade squamous intraepithelial lesions; HSIL—high-grade squamous intraepithelial lesions; n—number.
See this image and copyright information in PMC

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