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. 2023 Feb 25;55(2):98.
doi: 10.1007/s11250-023-03512-8.

Type 2 abomasal ulceration in cattle and buffalo: energy and lipid metabolic status, clinico-biochemical parameters, treatment, and prognostic indicators

Syed Ashaq Hussain  1   2 , Sanjeev Kumar Uppal  3 , Naresh Kumar Sood  4 , Jitender Mohindroo  5
Affiliations

Type 2 abomasal ulceration in cattle and buffalo: energy and lipid metabolic status, clinico-biochemical parameters, treatment, and prognostic indicators

Syed Ashaq Hussain et al. Trop Anim Health Prod. .

Abstract

Twenty nine animals (22 cattle and 7 buffaloes) having type 2 abomasal ulcer (AU2) were studied in this prospective investigation, along with a control group (n = 20). Signalment, history, clinical signs, and laboratory alterations were determined. Blood, rumen fluid, abomasal fluid, and fecal samples were collected at the time of presentation. Depressed behavior, anorexia, dehydration, melena, sparse feces, and mushy rumen with substantially reduced or nonexistent motility, tachycardia, and tachypnea were common clinical findings. Colic was observed in 58% of animals. While the neutrophil count was significantly greater, the mean of lymphocytes, hemoglobin, erythrocyte count, and hematocrit were all lower (p < 0.05) than the corresponding control values. In comparison to the control values, the levels of BHBA, NEFA, lactate, bilirubin, BUN, creatinine, LDH, CK, GGT, ALP, and AST were significantly higher but levels of proteins, cholesterol, Na, K, Cl, and calcium were lower (p < 0.05). In comparison to the control values, the other hemato-biochemical parameters did not differ substantially (p < 0.05). The rumen and abomasal pH were within the reference range while rumen chloride concentration was increased in majority of animals. Higher percentage (p < 0.05) of non-survivors showed left shift and toxic alterations in neutrophils than the survivors. As compared to the survivors, the non-survivors had higher (p < 0.05) BHBA, triglycerides, total bilirubin, AST, ALP, LDH, and lactate, and lower (p < 0.05) fibrinogen and calcium. The response to medical treatment was fair, long time survival rate was good, and there was no recurrence. The follow-up period was 28 months. After treatment, both the current and the subsequent lactation's milk production were unaffected.

Keywords: Bovine; Hemato-biochemical parameters; Prognosis; Survival; Treatment; Type 2 abomasal ulcer.

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References

    1. Abeni, F., Calamari, L., Stefanini, L., 2007. Metabolic conditions of lactating Friesian cows during the hot season in the Po valley 1. Blood indicators of heat stress. International Journal Biometeorology, 52, 87-96. - DOI
    1. Ahmed, A.F., Constable, P.D., Misk, N.A., 2001. Effect of an orally administered cimetidineand ranitidine on abomasal luminal pH in clinicallynormal milk-fed calves. American Journal of Veterinary Research, 62, 1531-1538. - DOI - PubMed
    1. Ahmed, A.F., Constable, P.D., Misk, N.A., 2002. Effect of an orally administered antacid agent containing aluminum hydroxide and magnesium hydroxide on abomasal luminal pH in clinically normal milk-fed calves. Journal of American Veterinary Medical Association, 220(1), 74-79. - DOI
    1. Aukema, J.J., Breukink, H.J., 1974. Abomasal ulcers in adult cattle with fatal hemorrhage. Cornell Veterinarian, 64, 303-317.
    1. Bobe, G., Young, J.W., Beitz, D.C., 2004. Pathology, etiology, prevention, and treatment of fatty liver in dairy cows. Journal of Dairy Science, 87, 3105-3124. - DOI - PubMed

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