Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Feb 25;28(1):102.
doi: 10.1186/s40001-023-00992-0.

A review of neurological side effects of COVID-19 vaccination

Roya Hosseini  1 , Nayere Askari  2   3
Affiliations
Review

A review of neurological side effects of COVID-19 vaccination

Roya Hosseini et al. Eur J Med Res. .

Abstract

Following the COVID-19 virus epidemic, extensive, coordinated international research has led to the rapid development of effective vaccines. Although vaccines are now considered the best way to achieve collective safety and control mortality, due to the critical situation, these vaccines have been issued the emergency use licenses and some of their potential subsequence side effects have been overlooked. At the same time, there are many reports of side effects after getting a COVID-19 vaccine. According to these reports, vaccination can have an adverse event, especially on nervous system. The most important and common complications are cerebrovascular disorders including cerebral venous sinus thrombosis, transient ischemic attack, intracerebral hemorrhage, ischemic stroke, and demyelinating disorders including transverse myelitis, first manifestation of MS, and neuromyelitis optica. These effects are often acute and transient, but they can be severe and even fatal in a few cases. Herein, we have provided a comprehensive review of documents reporting neurological side effects of COVID-19 vaccines in international databases from 2020 to 2022 and discussed neurological disorders possibly caused by vaccination.

Keywords: COVID-19; Myelitis; Neurological side effects; SARS Covid-2; Thrombosis; Vaccine.

PubMed Disclaimer

Conflict of interest statement

Not applicable.

Figures

Fig. 1
Fig. 1
Classification of neurological complications observed after COVID-19 vaccination
See this image and copyright information in PMC

References

    1. Garg RK, Paliwal VK. Spectrum of neurological complications following COVID-19 vaccination. Neurol Sci. 2021 doi: 10.1007/s10072-021-05662-9. - DOI - PMC - PubMed
    1. who.int. https://covid19.who.int/mapFilter=deaths. Accessed 13 Novr 2022
    1. Nagy A, Alhatlani B. An overview of current COVID-19 vaccine platforms. Comput Struct Biotechnol J. 2021;19:2508–2517. doi: 10.1016/j.csbj.2021.04.061. - DOI - PMC - PubMed
    1. Abraham G, Bhalala OG, de Bakker PI, Ripatti S, Inouye M. Towards a molecular systems model of coronary artery disease. Curr Cardiol Rep. 2014;16(6):1–10. doi: 10.1007/s11886-014-0488-1. - DOI - PMC - PubMed
    1. Al Khames Aga QA, Alkhaffaf WH, Hatem TH, Nassir KF, Batineh Y, Dahham AT, Shaban D, Al Khames Aga LA, Agha MY, Traqchi M. Safety of COVID-19 vaccines. J Med Virol. 2021;93(12):6588–6594. doi: 10.1002/jmv.27214. - DOI - PMC - PubMed

Substances