A new triple combination cystic fibrosis transmembrane regulator modulator

Lucy Perrem¹, Felix Ratjen²

Affiliations

¹ Division of Respiratory Medicine, The Hospital for Sick Children, Toronto, Canada; Department of Paediatrics, University of Toronto, Canada; Translational Medicine Program, SickKids Research Institute, Toronto, Canada.
² Division of Respiratory Medicine, The Hospital for Sick Children, Toronto, Canada; Department of Paediatrics, University of Toronto, Canada; Translational Medicine Program, SickKids Research Institute, Toronto, Canada. Electronic address: felix.ratjen@sickkids.ca.

PMID: 36842448
DOI: 10.1016/S2213-2600(23)00001-2

Comment

A new triple combination cystic fibrosis transmembrane regulator modulator

Lucy Perrem et al. Lancet Respir Med. 2023 Jun.

. 2023 Jun;11(6):499-500.

doi: 10.1016/S2213-2600(23)00001-2. Epub 2023 Feb 23.

Authors

Lucy Perrem¹, Felix Ratjen²

Affiliations

¹ Division of Respiratory Medicine, The Hospital for Sick Children, Toronto, Canada; Department of Paediatrics, University of Toronto, Canada; Translational Medicine Program, SickKids Research Institute, Toronto, Canada.
² Division of Respiratory Medicine, The Hospital for Sick Children, Toronto, Canada; Department of Paediatrics, University of Toronto, Canada; Translational Medicine Program, SickKids Research Institute, Toronto, Canada. Electronic address: felix.ratjen@sickkids.ca.

PMID: 36842448
DOI: 10.1016/S2213-2600(23)00001-2

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Conflict of interest statement

LP declares no competing interests. FR declares being principal investigator for grants, consulting, or honorarium for cystic fibrosis-related activities from Vertex and has acted as a consultant for Calithera on cystic fibrosis-related activities.

Comment on

Safety and efficacy of vanzacaftor-tezacaftor-deutivacaftor in adults with cystic fibrosis: randomised, double-blind, controlled, phase 2 trials.
Uluer AZ, MacGregor G, Azevedo P, Indihar V, Keating C, Mall MA, McKone EF, Ramsey BW, Rowe SM, Rubenstein RC, Taylor-Cousar JL, Tullis E, Yonker LM, Chu C, Lam AP, Nair N, Sosnay PR, Tian S, Van Goor F, Viswanathan L, Waltz D, Wang LT, Xi Y, Billings J, Horsley A; VX18-121-101; VX18-561-101 Study Groups. Uluer AZ, et al. Lancet Respir Med. 2023 Jun;11(6):550-562. doi: 10.1016/S2213-2600(22)00504-5. Epub 2023 Feb 23. Lancet Respir Med. 2023. PMID: 36842446 Clinical Trial.

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A new triple combination cystic fibrosis transmembrane regulator modulator

Affiliations

A new triple combination cystic fibrosis transmembrane regulator modulator

Authors

Affiliations

Conflict of interest statement

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Publication types

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LinkOut - more resources

Full Text Sources

Medical