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Review
. 2023 Apr;46(4):307-317.
doi: 10.1016/j.tins.2023.01.006. Epub 2023 Feb 24.

Alterations in pain during adolescence and puberty

Affiliations
Review

Alterations in pain during adolescence and puberty

Hadas Nahman-Averbuch et al. Trends Neurosci. 2023 Apr.

Abstract

During adolescence and puberty, alterations in pain, both experimental and clinical, are observed. In addition, adolescents undergo extensive biopsychosocial changes as they transition from childhood to adulthood. However, a better understanding of how the biopsychosocial changes during adolescence impact pain is needed to improve pain management and develop targeted pain interventions for adolescents. This review synthesizes the literature on alterations in pain during adolescence in humans, describes the potential biopsychosocial factors impacting pain during adolescence, and suggests future research directions to advance the understanding of the impact of adolescent development on pain.

Keywords: biopsychosocial; brain; development; hormones; nociception; sex.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests in relation to this work.

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