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Review
. 2023 Apr 30;58(S1):S1-S7.
doi: 10.5045/br.2023.2023004. Epub 2023 Feb 27.

Transfusion support in hematopoietic stem cell transplantation

Dong Wook Jekarl  1 , Jae Kwon Kim  1 , Jay Ho Han  1 , Howon Lee  1 , Jaeeun Yoo  2 , Jihyang Lim  3 , Yonggoo Kim  1
Affiliations
Review

Transfusion support in hematopoietic stem cell transplantation

Dong Wook Jekarl et al. Blood Res. .

Abstract

Transfusion support for hematopoietic stem cell transplantation (HSCT) is an essential part of supportive care, and compatible blood should be transfused into recipients. As leukocyte antigen (HLA) matching is considered first and as the blood group does not impede HSCT, major, minor, bidirectional, and RhD incompatibilities occur that might hinder transfusion and cause adverse events. Leukocyte reduction in blood products is frequently used, and irradiation should be performed for blood products, except for plasma. To mitigate incompatibility and adverse events, local transfusion guidelines, hospital transfusion committees, and patient management should be considered.

Keywords: ABO blood group; Hematopoietic stem cell transplantation; RhD blood group; Transfusion.

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Conflict of interest statement

Authors’ Disclosures of Potential Conflicts of Interest

No potential conflicts of interest relevant to this article were reported.

Figures

Fig. 1
Fig. 1
The attachment site of ABO blood group antigen and ABO blood group antigen formation. These figures are modified based on previous studies [1]. Reproduced from The Korean Society for Laboratory Medicine, Laboratory Medicine 6th edition, page 1063, Figure 92-1 with permission from The Korean Society for Laboratory Medicine.
See this image and copyright information in PMC

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