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. 2023 Feb 20;12(3):216-219.
doi: 10.1007/s13691-023-00598-7. eCollection 2023 Jul.

COVID arm that appeared in the contralateral upper extremity after mRNA-1273 booster inoculation

Tomomi Sanomachi  1 , Hitomi Sumiyoshi Okuma  1 , Kan Yonemori  1
Affiliations

COVID arm that appeared in the contralateral upper extremity after mRNA-1273 booster inoculation

Tomomi Sanomachi et al. Int Cancer Conf J. .

Erratum in

Abstract

We report the findings of a 60-year-old female patient with metastatic breast cancer who presented with severe edema and neuralgia in the contralateral arm after receiving the third COVID-19 vaccine dose. The patient did not report any reaction to the first two doses of the BNT162b2 (Pfizer-BioNTech) vaccine. However, after a booster dose with the mRNA-1273 (Moderna) vaccine, the patient developed a high fever persisting for one week after the shot, and sequential severe swelling, inflammation, and pain in the contralateral arm lasting for three weeks.

Keywords: COVID arm; Remote location; mRNA-1273 booster inoculation.

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Conflict of interest statement

Conflict of interestNo funding was provided for this study.

Figures

Fig. 1
Fig. 1
Photograph of swollen arm. Approximately three days after the third dose of mRNA-1273 vaccine, edema appeared in the left upper extremity. Heat and pain were observed in the same area. The image on the left shows the left upper extremity one week after vaccination. The image on the right shows the left upper extremity four weeks after vaccination
Fig. 2
Fig. 2
Graph of serum antibodies. Changes in serum antibodies before and after COVID-19 vaccination are shown. Blood antibodies that react specifically against the spike protein (S antigen) on the viral surface of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (SARS-CoV-2-S-IgG and SARS-CoV-2-S-IgM) and blood antibodies that react specifically against the nucleocapsid protein inside the virus (SARS-CoV-2-N-IgG) were tested with chemiluminescent enzyme immunoassay. The test kit was purchased from the Sysmex Corporation (Hyogo, Japan). The left vertical axis corresponds to S-IgG and the right vertical axis corresponds to N-IgG and S-IgM. SU/mL is the proprietary measurement unit of the Sysmex Corporation. The horizontal axis indicates the required number of days. There were four measurement points: before the patient’s first dose of COVID-19 vaccine, five weeks after her second dose of vaccine, seven months after her second dose of vaccine, and two weeks after the third dose of vaccine
Fig. 3
Fig. 3
Graph of WBC and CRP. Changes in WBC and CRP before and after the third COVID-19 vaccination are shown. The left vertical axis corresponds to WBC and the right vertical axis to CRP. The horizontal axis is the number of days before and after the third COVID-19 vaccination
See this image and copyright information in PMC

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