Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Dec 20:17:e29.
doi: 10.15420/ecr.2022.11. eCollection 2022 Feb.

Artificial Intelligence and Cardiovascular Risk Prediction: All That Glitters is not Gold

Affiliations
Review

Artificial Intelligence and Cardiovascular Risk Prediction: All That Glitters is not Gold

Mauro Chiarito et al. Eur Cardiol. .

Abstract

Artificial intelligence (AI) is a broad term referring to any automated systems that need 'intelligence' to carry out specific tasks. During the last decade, AI-based techniques have been gaining popularity in a vast range of biomedical fields, including the cardiovascular setting. Indeed, the dissemination of cardiovascular risk factors and the better prognosis of patients experiencing cardiovascular events resulted in an increase in the prevalence of cardiovascular disease (CVD), eliciting the need for precise identification of patients at increased risk for development and progression of CVD. AI-based predictive models may overcome some of the limitations that hinder the performance of classic regression models. Nonetheless, the successful application of AI in this field requires knowledge of the potential pitfalls of the AI techniques, to guarantee their safe and effective use in daily clinical practice. The aim of the present review is to summarise the pros and cons of different AI methods and their potential application in the cardiovascular field, with a focus on the development of predictive models and risk assessment tools.

Keywords: Artificial intelligence; cardiovascular disease; machine learning; risk prediction.

PubMed Disclaimer

Conflict of interest statement

Disclosure: GS reports grants from Boston Scientific and consulting fees from Abbott Vascular, Boston Scientific and Pfizer/BMS. All other authors have no conflicts of interest to declare.

Figures

Figure 1:
Figure 1:. Main Features Defining Machine Learning Algorithms and Issues That Could Influence Their Predictive Performance.
Figure 2:
Figure 2:. Main Applications of Machine Learning Methods in the Cardiovascular Setting.

Similar articles

Cited by

References

    1. Virani SS, Alonso A, Benjamin EJ et al. Heart disease and stroke statistics – 2020 update: a report from the American Heart Association. Circulation. 2020;141:e139–e596. doi: 10.1161/CIR.0000000000000746. - DOI - PubMed
    1. Nichols M, Townsend N, Scarborough P, Rayner M. Cardiovascular disease in Europe: epidemiological update. Eur Heart J. 2013;34:3028–34. doi: 10.1093/eurheartj/eht356. - DOI - PubMed
    1. Moran AE, Forouzanfar MH, Roth GA et al. Temporal trends in ischemic heart disease mortality in 21 world regions, 1980 to 2010: the Global Burden of Disease 2010 study. Circulation. 2014;129:1483–92. doi: 10.1161/CIRCULATIONAHA.113.004042. - DOI - PMC - PubMed
    1. GBD 2013 Mortality and Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;385:117–71. doi: 10.1016/S0140-6736(14)61682-2. - DOI - PMC - PubMed
    1. Mensah GA, Wei GS, Sorlie PD et al. Decline in cardiovascular mortality: possible causes and implications. Circ Res. 2017;120:366–80. doi: 10.1161/CIRCRESAHA.116.309115. - DOI - PMC - PubMed