Time-Restricted Feeding Enhances Early Atherosclerosis in Hypercholesterolemic Mice

Chang Pan^{1

2}, Beatriz Herrero-Fernandez^{3

4}, Celia Borja Almarcha^{1

2}, Raquel Gomez Bris^{3

4}, Virginia Zorita⁵, Angela Sáez^{3

6}, Sanne Lidewij Maas², Laura Pérez-Olivares^{1

2}, Andrea Herrero-Cervera¹, Patricia Lemnitzer², Kristof van Avondt^{1

2}, Carlos Silvestre-Roig^{1

2}, Jose Maria Gonzalez-Granado^{3

5

7

8}, Raphael Chevre^#^{1

2}, Oliver Soehnlein^#^{1

2

9}

Affiliations

¹ Institute of Experimental Pathology (ExPat), Center for Molecular Biology of Inflammation (ZMBE), Westfälische Wilhelms-Universität (WWU), Münster, Germany (C.P., C.B.A., L.P.-O. A.H.-C., K.v.A., C.S.-R., R.C., O.S.).
² Institute for Cardiovascular Prevention (IPEK), Ludwig Maximilian University, Munich, Germany (C.P., C.B.A., S.L.M., L.P.-O., P.L., K.v.A., C.S.-R., R.C., O.S.).
³ LamImSys Lab, Instituto de Investigación Sanitaria Hospital), Madrid, Spain (B.H.-F., R.G.B., A.S., J.M.G.-G.).
⁴ Departamento de Fisiología, Facultad de Medicina, Universidad Autónoma de Madrid (UAM), Spain (B.H.-F., R.G.B.).
⁵ Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (V.Z., J.M.G.-G.).
⁶ Facultad de Ciencias Experimentales, Universidad Francisco de Vitoria (UFV), Pozuelo de Alarcón, Madrid, Spain (A.S.).
⁷ Department of Immunology, Ophthalmology and ENT, School of Medicine, Universidad Complutense de Madrid, Spain (J.M.G.-G.).
⁸ CIBER de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain (J.M.G.-G.).
⁹ Department of Physiology and Pharmacology (FyFa), Karolinska Institute, Stockholm, Sweden (O.S.).

^# Contributed equally.

Chang Pan et al. Circulation. 2023.

. 2023 Feb 28;147(9):774-777.

doi: 10.1161/CIRCULATIONAHA.122.063184. Epub 2023 Feb 27.

¹ Institute of Experimental Pathology (ExPat), Center for Molecular Biology of Inflammation (ZMBE), Westfälische Wilhelms-Universität (WWU), Münster, Germany (C.P., C.B.A., L.P.-O. A.H.-C., K.v.A., C.S.-R., R.C., O.S.).
² Institute for Cardiovascular Prevention (IPEK), Ludwig Maximilian University, Munich, Germany (C.P., C.B.A., S.L.M., L.P.-O., P.L., K.v.A., C.S.-R., R.C., O.S.).
³ LamImSys Lab, Instituto de Investigación Sanitaria Hospital), Madrid, Spain (B.H.-F., R.G.B., A.S., J.M.G.-G.).
⁴ Departamento de Fisiología, Facultad de Medicina, Universidad Autónoma de Madrid (UAM), Spain (B.H.-F., R.G.B.).
⁵ Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (V.Z., J.M.G.-G.).
⁶ Facultad de Ciencias Experimentales, Universidad Francisco de Vitoria (UFV), Pozuelo de Alarcón, Madrid, Spain (A.S.).
⁷ Department of Immunology, Ophthalmology and ENT, School of Medicine, Universidad Complutense de Madrid, Spain (J.M.G.-G.).
⁸ CIBER de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain (J.M.G.-G.).
⁹ Department of Physiology and Pharmacology (FyFa), Karolinska Institute, Stockholm, Sweden (O.S.).

^# Contributed equally.

No abstract available

Keywords: atherosclerosis; diet, high-fat; hypercholesterolemia; intermittent fasting; non-alcoholic fatty liver disease.

Publication types