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Case Reports
. 2023 Feb-Mar;35(1):158-160.
doi: 10.55519/JAMC-01-10493.

Granular Cell Astrocytoma

Ayma Batool  1 , Azra Bashir  1 , Saira Javeed  1 , Samina Zaman  1 , Akhtar Sohail Chughtai  1
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Free article
Case Reports

Granular Cell Astrocytoma

Ayma Batool et al. J Ayub Med Coll Abbottabad. 2023 Feb-Mar.
Free article

Abstract

Granular cell astrocytoma (GCA) is a rare glial neoplasm composed of abundant granular cytoplasm gives immunoreactivity for GFAP and S100 stains. We report a case of GCA in a 64 years old male presented with history of fits, right sided weakness and loss of consciousness. The microscopy showed sheets of large cells with abundant eosinophilic granular cytoplasm. No high-grade features were seen. Its differential diagnosis includes most of the benign histiocytic conditions. Granular cell astrocytoma has an aggressive clinical course and its survival rate is less than 1 year. That's why early correct diagnosis is very essential.

Keywords: Granular cell Astrocytoma; Immunohistochemistry, GFAP.

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