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Case Reports
. 2023 Feb 13:31:e01713.
doi: 10.1016/j.idcr.2023.e01713. eCollection 2023.

Secondary syphilis in a 14-month-old girl and child-to-mother transmission

Alexandre Regueme  1 , Amélie Lesueur  1 , Benoît Catteau  2 , Célia Tillard  3 , Agnès Wacrenier  4 , Noémie Cartier  1 , Mouna Lazrek  1 , Aurélie Guigon  1 , Didier Hober  1 , Enagnon Kazali Alidjinou  1
Affiliations
Case Reports

Secondary syphilis in a 14-month-old girl and child-to-mother transmission

Alexandre Regueme et al. IDCases. .

Abstract

Syphilis cases in childhood are usually associated with congenital transmission. Acquired transmission is uncommon, and primarily related to sexual abuse or close contact/nursing with infected family members. We here describe a case of syphilis in a 14-month-old girl resulting from intrafamilial infection, with a subsequent transmission to her mother.

Keywords: Acquired syphilis; Child; Child-to-mother transmission; Intrafamilial infection.

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
Detection of spirochetes by immunohistochemistry in vulvar skin biopsy from the 14-month-old girl. Light microscopy of the vulva squamous epithelium showing an inflammatory infiltrate containing numerous spirochetes. The slide was labeled using anti-Treponema antibody (Biocare) with a red alkaline phosphatase revelation, and hematoxylin counter staining (X40 magnification).
Fig. 2
Fig. 2
X-ray of long bones. X-ray of lower limbs with arrows showing multiple periosteal appositions, alternating radiolucent and radiodense metaphyseal lines, and osteolytic lesions.
See this image and copyright information in PMC

References

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