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Practice Guideline
. 2023 Mar;16(1):50-67.
doi: 10.1111/jebm.12514. Epub 2023 Feb 28.

Evidence-based guideline for the prevention and management of perioperative infection

Qiaoyu Wang  1 , Mingnan Cao  1 , Hua Tao  2 , Zhimin Fei  3 , Xiufeng Huang  4 , Pixia Liang  5 , Baiyun Liu  5 , Jianping Liu  6 , Xiaoyang Lu  7 , Penglin Ma  8 , Shuyi Si  9 , Shuo Wang  5 , Yuewei Zhang  10 , Yingli Zheng  11 , Lei Zang  12 , Xiao Chen  13 , Zhanjun Dong  14 , Weihong Ge  15 , Wei Guo  16 , Xin Hu  17 , Xin Huang  18 , Ling Li  19 , Jianshu Liang  20 , Baoge Liu  21 , Dong Liu  22 , Linna Liu  23 , Songqing Liu  24 , Xianghong Liu  25 , Liyan Miao  26 , Haixia Ren  27 , Guangzhi Shi  28 , Luwen Shi  29 , Shumei Sun  30 , Xia Tao  31 , Rongsheng Tong  32 , Cheng Wang  33 , Bin Wang  34 , Jincheng Wang  35 , Jingwen Wang  36 , Xiaoling Wang  37 , Xiaoyan Wang  38 , Jian Xie  5 , Shouxia Xie  39 , Hua Yang  40 , Jianxin Yang  41 , Chao You  42 , Hongyi Zhang  10 , Yi Zhang  27 , Chengson Zhao  43 , Qingchun Zhao  44 , Jiangguo Zhu  26 , Bo Ji  45 , Ruichen Guo  25 , Chunhua Hang  46 , Xiaowei Xi  47 , Sheyu Li  48 , Zhicheng Gong  49 , Jianxin Zhou  28 , Rui Wang  50 , Zhigang Zhao  1
Affiliations
Practice Guideline

Evidence-based guideline for the prevention and management of perioperative infection

Qiaoyu Wang et al. J Evid Based Med. 2023 Mar.

Abstract

Background: We have updated the guideline for preventing and managing perioperative infection in China, given the global issues with antimicrobial resistance and the need to optimize antimicrobial usage and improve hospital infection control levels.

Methods: We conducted a comprehensive evaluation of the evidence for prevention and management of perioperative infection, based on the concepts of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. The strength of recommendations was graded and voted using the Delphi method and the nominal group technique. Revisions were made to the guidelines in response to feedback from the experts.

Results: There were 17 questions prepared, for which 37 recommendations were made. According to the GRADE system, we evaluated the body of evidence for each clinical question. Based on the meta-analysis results, recommendations were graded using the Delphi method to generate useful information.

Conclusions: This guideline provides evidence to perioperative antimicrobial prophylaxis that increased the rational use of prophylactic antimicrobial use, with substantial improvement in the risk-benefit trade-off.

Keywords: Delphi; GRADE; antimicrobials; guideline; perioperative infection.

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References

REFERENCES

    1. Berrios-Torres SI, Umscheid CA, Bratzler DW, et al. Centers for disease control and prevention guideline for the prevention of surgical site infection, 2017. JAMA Surg. 2017;152(8):784-91.
    1. Allegranzi B, Bagheri Nejad S, Combescure C, et al. Burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysis. Lancet. 2011;377(9761):228-41.
    1. Chinese Society of Surgical Infection and Intensive Care CSoS, Chinese Medical Association; Chinese College of Gastrointestinal Fistula Surgeons, Chinese College of Surgeons, Chinese Medical Doctor Association. Chinese guideline for the prevention of surgical site infection. Chin J Gastrointest Surg. 2019;22(4):301-14.
    1. Allegranzi B, Zayed B, Bischoff P, et al. New WHO recommendations on intraoperative and postoperative measures for surgical site infection prevention: an evidence-based global perspective. Lancet Infect Dis. 2016;16(12):e288-e303.
    1. Ban KA, Minei JP, Laronga C, et al. American College of Surgeons and Surgical Infection Society: Surgical Site Infection Guidelines, 2016 Update. J Am Coll Surg. 2017;224(1):59-74.

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