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Review
. 2023 Aug;38(6):529-536.
doi: 10.1080/08820538.2023.2181665. Epub 2023 Feb 28.

Combined Microinvasive Glaucoma Surgery - A Review of the Literature and Future Directions

Derek D Mai  1 , Zoe Ingram  1 , Blake Oberfeld  2 , David Solá-Del Valle  1
Affiliations
Free article
Review

Combined Microinvasive Glaucoma Surgery - A Review of the Literature and Future Directions

Derek D Mai et al. Semin Ophthalmol. 2023 Aug.
Free article

Abstract

The use of microinvasive invasive glaucoma surgery (MIGS) in the treatment of glaucoma has increased exponentially over the last 10 years. However, practice patterns vary widely given the relative newness of these technologies. Some surgeons perform two or more MIGS simultaneously, such as those that target aqueous production and those that target aqueous outflow. These combined MIGS (cMIGS) may result in lower intraocular pressure (IOP) and reduced medication burden as compared to single MIGS (sMIGS). Current evidence suggests some cMIGS are more effective in reducing medication burden for at least 12 months versus sMIGS. This review focuses on the current evidence related to the efficacy of cMIGS as well as novel combinations of standalone MIGS, limitations of the current literature, and future directions for research.

Keywords: CMIGS; Combination MIGS; Combined MIGS; ICE1; ICE2; PEcK.

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