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Editorial
. 2023 Mar 1;13(3):532-534.
doi: 10.1158/2159-8290.CD-22-1439.

Moving Forward Liquid Biopsy in Early Liver Cancer Detection

Christian Rolfo  1 , Alessandro Russo  2
Affiliations
Editorial

Moving Forward Liquid Biopsy in Early Liver Cancer Detection

Christian Rolfo et al. Cancer Discov. .

Abstract

Early cancer detection is an attractive and promising application for liquid biopsy that might revolutionize cancer screenings. In this issue of Cancer Discovery, Foda and colleagues expand the potential utility of a machine learning fragmentome-based model, called DELFI, for detecting liver cancer in high-risk patients. See related article by Foda et al., p. 616 (5).

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  • Detecting Liver Cancer Using Cell-Free DNA Fragmentomes.
    Foda ZH, Annapragada AV, Boyapati K, Bruhm DC, Vulpescu NA, Medina JE, Mathios D, Cristiano S, Niknafs N, Luu HT, Goggins MG, Anders RA, Sun J, Meta SH, Thomas DL, Kirk GD, Adleff V, Phallen J, Scharpf RB, Kim AK, Velculescu VE. Foda ZH, et al. Cancer Discov. 2023 Mar 1;13(3):616-631. doi: 10.1158/2159-8290.CD-22-0659. Cancer Discov. 2023. PMID: 36399356 Free PMC article.

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