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Comment
. 2023 Apr;22(4):268.
doi: 10.1038/d41573-023-00033-9.

PIKfyve inhibition rescues ALS pathology

Sarah Crunkhorn
Comment

PIKfyve inhibition rescues ALS pathology

Sarah Crunkhorn. Nat Rev Drug Discov. 2023 Apr.
No abstract available

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Comment on

  • PIKFYVE inhibition mitigates disease in models of diverse forms of ALS.
    Hung ST, Linares GR, Chang WH, Eoh Y, Krishnan G, Mendonca S, Hong S, Shi Y, Santana M, Kueth C, Macklin-Isquierdo S, Perry S, Duhaime S, Maios C, Chang J, Perez J, Couto A, Lai J, Li Y, Alworth SV, Hendricks E, Wang Y, Zlokovic BV, Dickman DK, Parker JA, Zarnescu DC, Gao FB, Ichida JK. Hung ST, et al. Cell. 2023 Feb 16;186(4):786-802.e28. doi: 10.1016/j.cell.2023.01.005. Epub 2023 Feb 7. Cell. 2023. PMID: 36754049 Free PMC article.

References

    1. Hung, S-T. et al. PIKFYVE inhibition mitigates disease in models of diverse forms of ALS. Cell 186, 786–802.e28 (2023) - PubMed - DOI

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