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Case Reports
. 2023 Feb 23:16:11795476231157244.
doi: 10.1177/11795476231157244. eCollection 2023.

Monotherapy With a Non-Hormonal Centella Asiatica, Hyaluronic Acid, and Prebiotic-Based Vaginal Gel in Women With Bacterial Vaginosis: Case Series

Affiliations
Case Reports

Monotherapy With a Non-Hormonal Centella Asiatica, Hyaluronic Acid, and Prebiotic-Based Vaginal Gel in Women With Bacterial Vaginosis: Case Series

Aaron Jodar et al. Clin Med Insights Case Rep. .

Abstract

Bacterial vaginosis (BV) affects nearly one-third of women worldwide and may predispose patients to sexually transmitted infections or pelvic inflammatory disease. Currently recommended treatment is based on antibiotic use, which poses problems such as antibiotic resistance and the development of secondary vaginal candidiasis. Palomacare® is a non-hormonal vaginal gel containing hyaluronic acid, Centella asiatica and prebiotics, with repairing and moisturizing properties used for dysbiosis healing as an adjuvant treatment. A series of 3 cases using the vaginal gel as a monotherapy showed that symptoms improved and even disappeared in women with initial or recurrent BV, suggesting that this vaginal gel is effective for BV monotherapy in women of reproductive age.

Keywords: Bacterial vaginosis; hyaluronic acid and prebiotic-based gel; monotherapy; non-hormonal Centella asiatica; prebiotic.

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Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Macroscopical appearance of vaginal tissue during speculoscopy from case 1 patient (A) before and (B) after treatment with the non-hormonal Centella asiatica, hyaluronic acid and prebiotic-based vaginal gel.
Figure 2.
Figure 2.
Macroscopical appearance of vaginal tissue during speculoscopy from case 2 patient (A) before and (B) after treatment with the non-hormonal Centella asiatica, hyaluronic acid, and prebiotic-based vaginal gel.
Figure 3.
Figure 3.
Macroscopical appearance of vaginal tissue during speculoscopy from case 3 patient (A) before and (B) after treatment with the non-hormonal Centella asiatica, hyaluronic acid, and prebiotic-based vaginal gel.

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