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. 2022;8(3):237-239.

First case of posterior cranial fossa myopericytoma treated with a combined microsurgery and stereotactic radiosurgery approach: Case report and literature review

Riccardo Lavezzo  1 , Salima Magrini  2 , Marta Rossetto  2 , Irene Coati  3 , Angelo P Dei Tos  4 , Matilde Cazzagon  5 , Nicola Cavasin  5 , Paolo M Polloniato  6 , Anna D'Amico  7 , Michele Longhi  1 , Francesco Sala  1 , Antonio Nicolato  7
Affiliations

First case of posterior cranial fossa myopericytoma treated with a combined microsurgery and stereotactic radiosurgery approach: Case report and literature review

Riccardo Lavezzo et al. J Radiosurg SBRT. 2022.
No abstract available

Keywords: Gamma Knife radiosurgery; intracranial tumor; myopericytoma; posterior cranial fossa; stereotactic radiosurgery.

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Figures

Figure 1
Figure 1
A) CT and MRI on admission: CT scan showing a right infratentorial slightly hyperdense lesion (A1), DWI sequence showing no diffusion restriction (A2), T2-weighted images showing hyperintense lesion with hypointense spots and stripes (A3), T1-weighted images showing hypointense lesion with hyperintense spots (A4), post-contrast T1-weighted images showing strong and homogeneous enhancement (A5), perfusion MRI showing increased perfusion parameters (A6). B) Post-operative 3-month control MRI showing tumor recurrence: T2-weighted images (B1), post-contrast T1-weighted images, axial view (B2), post-contrast T1-weighted images, coronal view (B3). C) Postradiosurgery 2-year control MRI showing complete disappearance of the tumor: T2-weighted images (C1), T1-weighted images (C2), post-contrast T1-weighted images (C3). D) Histopathologic analysis: hematoxylin and eosin stain showing vasoformative neoplasia composed by vessels surrounded by ovoid, spindle-shaped cells (D1-2), high magnification of tumor myoid cells positive for smooth muscle actin (D3), high magnification of endothelial cells expressing CD34, while perivascular myoid cells are negative (D4), anti-endomysial antibody negative (D5), progesterone receptor negative (D6), glial fibrillary acidic protein negative (D7), inhibin-alpha negative (D8). E) Gamma-Knife treatment planning showing the 15.0 Gy prescription dose line.
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References

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