Investigation the phytochemical profiling and therapeutic evaluation of ginger root powder against hypercholesterolemia and obesity

Abstract

Obesity is a metabolic disease that is characterized by increased caloric intake and decreased physical activity. Ginger (Zingiber officinale) is used as a spice that has potential role as an alternative medicine in a range of many diseases. The current research was carried out to explore the anti-obesity potential of ginger root powder. For this, the chemical and phytochemical characterization of ginger root powder were analyzed. Results showed that it contains moisture, ash content, crude fat, crude protein, crude fiber and nitrogen free extract 6.22±0.35, 6.37±0.18, 5.31±0.46, 1.37±0.15, 10.48±0.67 and 64.78±11.33mg/dl, respectively. Furthermore, the ginger root powder was given in the form of capsules to obese patients for the already designed treatment groups. The experimental groups (G₁ and G₂) were given ginger root powder capsules (3g) to G₁ group and (6g) was given to G₂ group for the time of 60 days. Results unveiled that G₂ group showed highly significant change on waist to hip ratio (WHR) and the other parameters like (BMI, Body weight) and cholesterol showed slightly - significant change on both groups G₁ and G₂. It can be considered as an arsenal for fight against the health problems that have been raised from the obesity.