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Review
. 2023 Feb 20;18(14):1135-1149.
doi: 10.4244/EIJ-D-22-00070.

Transcatheter interventions for heart failure

Affiliations
Review

Transcatheter interventions for heart failure

Azeem Latib et al. EuroIntervention. .

Abstract

Despite significant advances in the medical management of patients living with heart failure, there continues to be significant morbidity and mortality associated with the condition. There is a growing need for research and development of additional modalities to fill the management and treatment gaps, reduce hospitalisations and improve the quality of life for patients living with heart failure. In the last decade, there has been a rapid rise in the use of non-valvular catheter-based therapies for the management of chronic heart failure to complement existing guideline-directed management. They target well-defined mechanistic and pathophysiological processes critical to the progression of heart failure including left ventricular remodelling, neurohumoral activation, and congestion. In this review, we will explore the physiology, rationale, and current stages of the clinical development of the existing procedures.

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Conflict of interest statement

A. Latib has served on advisory boards or as a consultant for Medtronic, Boston Scientific, Philips, Edwards Lifesciences, Abbott, and Ancora Heart. U.P. Jorde has served on advisory boards for Edwards Lifesciences and Abbott; has been a consultant for Edwards Lifesciences and Abbott and receives travel support from Ancora Heart. W.T. Abraham has received personal fees from Vectorious Medical Technologies and V-Wave. J. Bartunek serves on the Trial Steering Committee for Occlutech and as a member of the Clinical Events Committees and Data Safety Monitoring Boards of the Vectorious HF trials. He receives personal fees from Occlutech. M.H. Mustehsan has no conflicts of interest to declare.

Figures

Central illustration
Central illustration. Novel therapies for the management of heart failure by mechanism.
Yellow/green: Devices for management of chronic heart failure. Blue/purple: Devices for management of acute decompensated heart failure. CRS: cardiorenal syndrome
Figure 1
Figure 1. Implantable haemodynamic monitors.
A) CardioMEMS (adapted from Abbott). B) Cordella (adapted from Endotronix). C) V-LAP (adapted from Vectorious Medical Technologies)
Figure 2
Figure 2. Interatrial shunt devices.
A) InterAtrial Shunt Device (adapted from Corvia Medical). B) V-Wave Shunt System (adapted from V-Wave). C) Atrial Flow Regulator (adapted from Occlutech). D) Transcatheter Atrial Shunt System (adapted from Edwards Lifesciences)
Figure 3
Figure 3. Devices for renal artery perfusion.
A) Aortix Percutaneous Mechanical Circulatory Support System (adapted from Procyrion). B) Reitan Catheter Pump (adapted from Cardiobridge). C) Second Heart Assist Device (adapted from Second Heart Assist)

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