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Comment
. 2023 May;19(5):259-260.
doi: 10.1038/s41582-023-00790-6.

Viral pathogens increase risk of neurodegenerative disease

Britanie M Blackhurst  1 , Kristen E Funk  2
Affiliations
Comment

Viral pathogens increase risk of neurodegenerative disease

Britanie M Blackhurst et al. Nat Rev Neurol. 2023 May.

Erratum in

Abstract

A new study, drawing on data from national biobanks, adds to the growing evidence that exposure to common viral pathogens increases the risk of Alzheimer disease and other neurodegenerative diseases. These findings might provide insights into the initiating factors that lead to neurodegeneration.

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Conflict of interest statement

The authors declare no competing interests.

Comment on

References

    1. Lotz, S. K., Blackhurst, B. M., Reagin, K. L. & Funk, K. E. Microbial infections are a risk factor for neurodegenerative diseases. Front. Cell. Neurosci.15, 691136 (2021). - DOI - PMC - PubMed
    1. Griciuc, A. & Tanzi, R. E. The role of innate immune genes in Alzheimer’s disease. Curr. Opin. Neurol.34, 228–236 (2021). - DOI - PMC - PubMed
    1. Parhizkar, S. & Holtzman, D. M. APOE mediated neuroinflammation and neurodegeneration in Alzheimer’s disease. Semin. Immunol.59, 101594 (2022). - DOI - PMC - PubMed
    1. Levine, K. S. et al. Virus exposure and neurodegenerative disease risk across national biobanks. Neuron10.1016/j.neuron.2022.12.029 (2023). - DOI - PMC - PubMed
    1. Bjornevik, K. et al. Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis. Science375, 296–301 (2022). - DOI - PubMed

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