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Editorial
. 2023 Feb 14:10:1142656.
doi: 10.3389/fmolb.2023.1142656. eCollection 2023.

Editorial: Intersection of biophysical and structural approaches in vaccine design

Christopher P Ptak  1 , Ching-Lin Hsieh  2   3 , James A Garnett  4 , Rino Rappuoli  5   6   7 , Yi-Pin Lin  8   9
Affiliations
Editorial

Editorial: Intersection of biophysical and structural approaches in vaccine design

Christopher P Ptak et al. Front Mol Biosci. .
No abstract available

Keywords: antigen; protein engineering; stability; structural biology; vaccine design.

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Conflict of interest statement

C-LH is employed by Sanofi S.A. RR is an employee of the GSK group of companies. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Comment on

  • Editorial on the Research Topic Intersection of biophysical and structural approaches in vaccine design

References

    1. Graham B. S., Gilman M. S. A., McLellan J. S. (2019). Structure-based vaccine antigen design. Annu. Rev. Med. 70, 91–104. 10.1146/annurev-med-121217-094234 - DOI - PMC - PubMed
    1. Hsieh C. L., McLellan J. S. (2022). Protein engineering responses to the COVID-19 pandemic. Curr. Opin. Struct. Biol. 74, 102385. 10.1016/j.sbi.2022.102385 - DOI - PMC - PubMed
    1. Malito E., Biancucci M., Faleri A., Ferlenghi I., Scarselli M., Maruggi G., et al. (2014). Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody. Proc. Natl. Acad. Sci. U. S. A. 111 (48), 17128–17133. 10.1073/pnas.1419686111 - DOI - PMC - PubMed
    1. Rappuoli R., Bottomley M. J., D'Oro U., Finco O., De Gregorio E. (2016). Reverse vaccinology 2.0: Human immunology instructs vaccine antigen design. J. Exp. Med. 213 (4), 469–481. 10.1084/jem.20151960 - DOI - PMC - PubMed
    1. Rappuoli R. (2021). COVID-19 vaccines: Sprint predicted a decade ago. Nature 590 (7844), 36. 10.1038/d41586-021-00272-z - DOI - PubMed

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