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Case Reports
. 2023 Feb 21:2023:9647892.
doi: 10.1155/2023/9647892. eCollection 2023.

Malignant Melanoma Presenting as Spinal Cord and Pleural Lesions

Affiliations
Case Reports

Malignant Melanoma Presenting as Spinal Cord and Pleural Lesions

Aysha Albastaki et al. Case Rep Oncol Med. .

Abstract

Primary spinal cord melanoma (PSCM) and primary pleural melanoma (PPM) are extremely rare entities with scarce cases reported in the literature. We present a case of a 54-year-old male diagnosed with possible primary pleural melanoma and primary spinal melanoma, managed with partial surgical resection, postoperative radiotherapy, and chemotherapy consisting of Ipilimumab, nivolumab, and temozolomide. This leads to decreased symptoms and improved quality of life of the patient. In this case report, we review the literature on PSCM and PPM in detail, addressing the pertinent clinical aspects as well as current and upcoming therapeutic options.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
T2-weighted sagittal MR of the neck showing the spinal lesion at the level of T5.
Figure 2
Figure 2
T2-weighted sagittal (view/section) MRI of the neck showing the pleural lesion.
Figure 3
Figure 3
High-resolution chest CT shows a pulmonary nodule in the right middle lung lobe denoting pulmonary metastasis.
Figure 4
Figure 4
High-resolution chest CT showing another left lower lung lobe paracardiac lung mass denoting another metastatic lesion.

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References

    1. Markovic S. N., Erickson L. A., Flotte T. J., et al. Metastatic malignant melanoma. Giornale Italiano di Dermatologia e Venereologia . 2009;144(1):1–26. - PubMed
    1. Chang A. E., Karnell L. H., Menck H. R. The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84,836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society. Cancer . 1998;83(8):1664–1678. doi: 10.1002/(SICI)1097-0142(19981015)83:8<1664::AID-CNCR23>3.0.CO;2-G. - DOI - PubMed
    1. Murakami K., Tobino K., Yamaji Y., et al. Primary pleural melanoma: a case report and literature review. Internal Medicine . 2019;58(22):3273–3276. doi: 10.2169/internalmedicine.3111-19. - DOI - PMC - PubMed
    1. Perera E., Gnaneswaran N., Jennens R., Sinclair R. Malignant melanoma. Healthcare . 2014;2(1):1–19. - PMC - PubMed
    1. Linos E., Swetter S. M., Cockburn M. G., Colditz G. A., Clarke C. A. Increasing burden of melanoma in the United States. The Journal of Investigative Dermatology . 2009;129(7):1666–1674. doi: 10.1038/jid.2008.423. - DOI - PMC - PubMed

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