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. 2023 Oct;24(Suppl 1):1-7.
doi: 10.1007/s11121-023-01503-7. Epub 2023 Mar 4.

Introduction to Helping to End Addiction Long-Term Prevention Cooperative: Overview and Strategies

Ty A Ridenour  1 , Lissette M Saavedra  2 , Claudia-Santi F Fernandes  3 , Jessica Duncan Cance  2 , Phillip W Graham  2 , Barbara A Oudekerk  4
Affiliations

Introduction to Helping to End Addiction Long-Term Prevention Cooperative: Overview and Strategies

Ty A Ridenour et al. Prev Sci. 2023 Oct.

Abstract

This supplemental issue describes the individual studies and collaborative efforts of the Helping to End Addiction Long-term Prevention Cooperative's (HPC's) innovative approaches to rapidly develop evidence-based prevention programs for widespread dissemination. This introduction succinctly reviews (1) the context that demands the rapid development of efficacious prevention programs and their scale-ups, (2) the unique objectives of the individual HPC research projects, and (3) collective efforts to harmonize research across studies to advance the prevention of opioid misuse and gain insight into opioid misuse etiology to inform improvements in preventive interventions. At the conclusion of HPC studies, we anticipate the availability of multiple evidence-based programs to prevent opioid misuse and use disorder for persons who experience particular sources of risk and for delivery in settings where prevention has traditionally been lacking. By harmonizing and coordinating efforts across 10 distinct outcomes studies of prevention programs and making data available for analysis by non-HPC researchers, the HPC's efficacy and etiology evidence will far surpass the additive contributions of 10 individual research projects.

Keywords: Adolescents; Helping to end addiction long-term; Opioid misuse; Opioid use disorder; Prevention; Young adults.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

References

    1. Bonar, E. E., Coughlin, L., Roche, J. S., Philyaw-Kotov, M. L., Bixler, E. A., Sinelnikov, S., & Walton, M. A. (2020). Prescription opioid misuse among adolescents and emerging adults in the United States: A scoping review. Preventive Medicine, 132, 105972. 10.1016/j.ypmed.2019.105972 - PMC - PubMed
    1. Cano, M. (2021). Racial/ethnic differences in US drug overdose mortality, 2017–2018. Addictive Behaviours, 112, 106625. 10.1016/j.addbeh.2020.106625 - PubMed
    1. Center for Behavioral Health Statistics and Quality. (2021). Racial/ethnic differences in substance use, substance use disorders, and substance use treatment utilization among people aged 12 or older (2015-2019). (Publication No. PEP21-07-01-001). Substance Abuse and Mental Health Services Administration. Retrieved February 2, 2023, from https://www.samhsa.gov/data/sites/default/files/reports/rpt35326/2021NSD...
    1. Ciccarone D. The rise of illicit fentanyls, stimulants and the fourth wave of the opioid overdose crisis. Current Opinion in Psychiatry. 2021;34(4):344–350. doi: 10.1097/YCO.0000000000000717. - DOI - PMC - PubMed
    1. HEAL Prevention Cooperative (HPC). (2021). HPC profiles. National Institutes of Health. Retrieved January 10 2022, from, https://heal.nih.gov/files/2021-12/NIH_HEAL_Profiles_11%20%282%29%20%281...

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