The sphingosine-1-phosphate receptor agonist etrasimod in ulcerative colitis
- PMID: 36871570
- DOI: 10.1016/S0140-6736(23)00228-3
The sphingosine-1-phosphate receptor agonist etrasimod in ulcerative colitis
Conflict of interest statement
RA reports grants for research support (related to treatment of ulcerative colitis broadly) from InDex Pharmaceuticals; consulting fees (related to treatment of ulcerative colitis broadly) from InDex Pharmaceuticals; honoraria for lectures (all related to treatment of ulcerative colitis broadly) from AbbVie, Amgen, Arena Pharmaceuticals (related to etrasimod), Biogen, Boehringer Ingelheim, Bristol-Myers Squibb, Celgene, Celltrion Healthcare, Falk Foundation, Fresenius Kabi, Galapagos, InDex Pharmaceuticals, Janssen-Cilag, Lilly, MSD, Roche Pharma, Samsung Bioepsis, and Takeda Pharma; support for attending meetings and travel from Janssen-Cilag; and advisory board fees (all related to treatment of ulcerative colitis broadly) from AbbVie, Arena Pharmaceuticals (related to etrasimod), Biogen, Boehringer Ingelheim, Bristol-Myers Squibb, Celgene, Celltrion Healthcare, Galapagos, Gilead, InDex Pharmaceuticals, Janssen-Cilag, Kliniksa Pharmaceuticals, Lilly, Pandion Therapeutics, Roche Pharma, Samsung Bioepsis, Takeda Pharma, and Viatris. MFN reports consulting fees (related to treatment of ulcerative colitis broadly) from AbbVie, MSD, Takeda, Boehringer, Roche, Pfizer, Janssen, PPD, and Pentax.
Comment on
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Etrasimod as induction and maintenance therapy for ulcerative colitis (ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies.Lancet. 2023 Apr 8;401(10383):1159-1171. doi: 10.1016/S0140-6736(23)00061-2. Epub 2023 Mar 2. Lancet. 2023. PMID: 36871574 Clinical Trial.
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