Review

. 2023 Jun;65(6):e757-e764.

doi: 10.1016/j.jpainsymman.2023.02.319. Epub 2023 Mar 5.

Community Informed Recruitment: A Promising Method to Enhance Clinical Trial Participation

Shena Gazaway¹, Marie Bakitas², Felicia Underwood³, Christiana Ekelem³, Marlee Duffie⁴, Sheila McCormick⁵, Vantrice Heard⁴, Audrey Colvin⁶, Ronit Elk³

Affiliations

¹ School of Nursing, University of Alabama at Birmingham (S.G., M.B.,), Birmingham, AL, USA; Center for Palliative and Supportive Care, University of Alabama at Birmingham (S.G., M.B., F.U., C.E., M.D., S.M., V.H., R.E.), Birmingham, AL, USA. Electronic address: gazaways@uab.edu.
² School of Nursing, University of Alabama at Birmingham (S.G., M.B.,), Birmingham, AL, USA; Center for Palliative and Supportive Care, University of Alabama at Birmingham (S.G., M.B., F.U., C.E., M.D., S.M., V.H., R.E.), Birmingham, AL, USA; Division of Geriatrics, School of Medicine, University of Alabama at Birmingham (M.B., F.U., C.E., R.E.), Birmingham, AL, USA.
³ Center for Palliative and Supportive Care, University of Alabama at Birmingham (S.G., M.B., F.U., C.E., M.D., S.M., V.H., R.E.), Birmingham, AL, USA; Division of Geriatrics, School of Medicine, University of Alabama at Birmingham (M.B., F.U., C.E., R.E.), Birmingham, AL, USA.
⁴ Center for Palliative and Supportive Care, University of Alabama at Birmingham (S.G., M.B., F.U., C.E., M.D., S.M., V.H., R.E.), Birmingham, AL, USA; Russell Medical Center (M.D., V.H.), Alexander City, AL, USA.
⁵ Center for Palliative and Supportive Care, University of Alabama at Birmingham (S.G., M.B., F.U., C.E., M.D., S.M., V.H., R.E.), Birmingham, AL, USA; Aiken Regional Medical Center (S.M.), Aiken, SC, USA.
⁶ Alexander City, AL.

PMID: 36871774
PMCID: PMC10192118
DOI: 10.1016/j.jpainsymman.2023.02.319

Review

Community Informed Recruitment: A Promising Method to Enhance Clinical Trial Participation

Shena Gazaway et al. J Pain Symptom Manage. 2023 Jun.

. 2023 Jun;65(6):e757-e764.

doi: 10.1016/j.jpainsymman.2023.02.319. Epub 2023 Mar 5.

Authors

Shena Gazaway¹, Marie Bakitas², Felicia Underwood³, Christiana Ekelem³, Marlee Duffie⁴, Sheila McCormick⁵, Vantrice Heard⁴, Audrey Colvin⁶, Ronit Elk³

Affiliations

¹ School of Nursing, University of Alabama at Birmingham (S.G., M.B.,), Birmingham, AL, USA; Center for Palliative and Supportive Care, University of Alabama at Birmingham (S.G., M.B., F.U., C.E., M.D., S.M., V.H., R.E.), Birmingham, AL, USA. Electronic address: gazaways@uab.edu.
² School of Nursing, University of Alabama at Birmingham (S.G., M.B.,), Birmingham, AL, USA; Center for Palliative and Supportive Care, University of Alabama at Birmingham (S.G., M.B., F.U., C.E., M.D., S.M., V.H., R.E.), Birmingham, AL, USA; Division of Geriatrics, School of Medicine, University of Alabama at Birmingham (M.B., F.U., C.E., R.E.), Birmingham, AL, USA.
³ Center for Palliative and Supportive Care, University of Alabama at Birmingham (S.G., M.B., F.U., C.E., M.D., S.M., V.H., R.E.), Birmingham, AL, USA; Division of Geriatrics, School of Medicine, University of Alabama at Birmingham (M.B., F.U., C.E., R.E.), Birmingham, AL, USA.
⁴ Center for Palliative and Supportive Care, University of Alabama at Birmingham (S.G., M.B., F.U., C.E., M.D., S.M., V.H., R.E.), Birmingham, AL, USA; Russell Medical Center (M.D., V.H.), Alexander City, AL, USA.
⁵ Center for Palliative and Supportive Care, University of Alabama at Birmingham (S.G., M.B., F.U., C.E., M.D., S.M., V.H., R.E.), Birmingham, AL, USA; Aiken Regional Medical Center (S.M.), Aiken, SC, USA.
⁶ Alexander City, AL.

PMID: 36871774
PMCID: PMC10192118
DOI: 10.1016/j.jpainsymman.2023.02.319

Abstract

Context: Low recruitment rates in palliative care clinical trials amongst Black and rural individuals have been attributed to lack of trust and procedural barriers. Community engagement strategies have increased clinical trial participation of under-represented populations.

Objective: Describe a successful community-engaged recruitment strategy in an ongoing multi-site randomized clinical trial (RCT).

Study design and methods: Using community-based participatory research principles and input from a prior pilot study's community advisory group (CAG), we designed a novel recruitment strategy for Community Tele-Pal, a three-site, culturally based palliative care tele-consult RCT for Black and White seriously ill inpatients and their family caregivers. Local site CAGs helped design and implement a recruitment strategy in which a CAG member accompanied the study coordinators to introduce the study to eligible patients. Initially, CAG members could not accompany study coordinators in person due to pandemic restrictions. Hence, they created videos of themselves introducing the study, just as they would have done in person. We examined outcomes to date by the three recruitment methods and race.

Results: Of the 2879 patients screened, 228 were eligible and approached. Overall, the proportions of patients who consented 102 (44.7%) vs. not consented 126 (55.3%) were similar by race- White (consented= 75 [44.1%]) vs; Black (consented = 27 [46.6%]). Proportionally, consent rates favored CAG-involved methods: coordinator only- 47 approached and 13 (12.7%) consented vs. coordinator/CAG video-105 approached and 60 (58.8%) consented.

Conclusion: A novel community-enhanced recruitment strategy demonstrated the potential to increase clinical trial participation from historically under-represented populations.

Keywords: Community-enhanced recruitment methods; black participants; randomized control trial participant recruitment; rural participants.

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Conflict of interest statement

Conflict of Interest Disclosure: The authors have no relevant conflicts of interest to disclose. The opinions presented here are those of the authors and do not reflect those of their funding agencies.

Figures

**Figure 1.. Community Tele-pal CONSORT Diagram.**
Electronic Medical Records Screened (EMR)

**Figure 2.**
Rate of Consent vs. Not Consent by Race and Recruitment Method CAG – Community Advisory Group Member

See this image and copyright information in PMC

References

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Community Informed Recruitment: A Promising Method to Enhance Clinical Trial Participation

Affiliations

Community Informed Recruitment: A Promising Method to Enhance Clinical Trial Participation

Authors

Affiliations

Abstract

Conflict of interest statement

Figures

References

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

Medical