Impact of switching total bilirubin assays on the classification of neonates at high risk for hyperbilirubinemia

Saranya Kittanakom^{1

2}, Jennifer Shea^{3

4}, Felix Leung^{2

5}, Vinh Ly¹, Sinthu Panchadcharadevan¹, Sangeet Kathuria¹, Ivor Margolis¹, Vilte Barakauskas⁶, Peter A Kavsak⁷

Affiliations

¹ William Osler Health System, Brampton, ON, Canada.
² Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
³ Department of Laboratory Medicine, Saint John Regional Hospital, Horizon Health Network, Saint John, NB, Canada.
⁴ Department of Pathology, Dalhousie University, Halifax, NS, Canada.
⁵ Department of Pathology and Laboratory Medicine, Sinai Health System, Toronto, ON, Canada.
⁶ Department of Pathology and Laboratory Medicine, BC Children's and Women's Hospital, Vancouver, BC, Canada.
⁷ Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.

Saranya Kittanakom et al. Clin Chem Lab Med. 2023.

. 2023 Mar 6;61(9):e175-e178.

doi: 10.1515/cclm-2023-0111. Print 2023 Aug 28.

Saranya Kittanakom^{1

2}, Jennifer Shea^{3

4}, Felix Leung^{2

5}, Vinh Ly¹, Sinthu Panchadcharadevan¹, Sangeet Kathuria¹, Ivor Margolis¹, Vilte Barakauskas⁶, Peter A Kavsak⁷

¹ William Osler Health System, Brampton, ON, Canada.
² Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
³ Department of Laboratory Medicine, Saint John Regional Hospital, Horizon Health Network, Saint John, NB, Canada.
⁴ Department of Pathology, Dalhousie University, Halifax, NS, Canada.
⁵ Department of Pathology and Laboratory Medicine, Sinai Health System, Toronto, ON, Canada.
⁶ Department of Pathology and Laboratory Medicine, BC Children's and Women's Hospital, Vancouver, BC, Canada.
⁷ Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.

No abstract available

Keywords: neonate; phototherapy; total bilirubin.

References

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1. Barrington, KJ, Sankaran, K, Canadian Paediatric Society, Fetus and Newborn Committee . Guidelines for detection, management and prevention of hyperbilirubinemia in term and late preterm newborn infants. https://cps.ca/en/documents/position/hyperbilirubinemia-newborn [Accessed 12 Dec 2022].
1. Bahr, TM, Henry, E, Christensen, RD, Minton, SD, Bhutani, VK. A new hour-specific serum bilirubin nomogram for neonates ≥ 35 weeks of gestation. J Pediatr 2021;236:28–33.e1. https://doi.org/10.1016/j.jpeds.2021.05.039 . - DOI
1. Greene, DN, Liang, J, Holmes, DT, Resch, A, Lorey, TS. Neonatal total bilirubin measurements: still room for harmonization. Clin Biochem 2014;47:1112–5. https://doi.org/10.1016/j.clinbiochem.2014.04.001 . - DOI
1. Lo, SF, Doumas, BT. The status of bilirubin measurements in U.S. laboratories: why is accuracy elusive? Semin Perinatol 2011;35:141–7. https://doi.org/10.1053/j.semperi.2011.02.008 . - DOI