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. 2023;16(1):3-9.
doi: 10.3233/PRM-230003.

A critical evaluation of oral baclofen in pediatric patients with cerebral palsy

Matthew J McLaughlin  1 , Mark T Fisher  1
Affiliations

A critical evaluation of oral baclofen in pediatric patients with cerebral palsy

Matthew J McLaughlin et al. J Pediatr Rehabil Med. 2023.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Dr. McLaughlin receives funding from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (1R03HD107642-01).

Figures

Fig. 1
Fig. 1
Proposed mechanism of baclofen action serving as a competitive antagonist at the GABA-B receptor sites.
Fig. 2
Fig. 2
Oral baclofen weight-corrected clearance differences between wild-type (grey dots) and heterogenous (white dots) children with cerebral palsy. This figure is reproduced with permission from the author per Elsevier’s retained author rights [17].
Fig. 3
Fig. 3
Allometric scaling to approximate organ size comparing the wild-type (grey dots) to the heterogenous (white dots) patients with cerebral palsy. This figure is reproduced with permission from the author per Elsevier’s retained author rights [17].
See this image and copyright information in PMC

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