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. 2023 Jan 9:51:101082.
doi: 10.1016/j.nmni.2023.101082. eCollection 2023 Jan.

First report of CrpP prevalence in a South American country

Affiliations

First report of CrpP prevalence in a South American country

Joaquim Ruiz et al. New Microbes New Infect. .

Abstract

The presence of crpP was established in 201 Pseudomonas aeruginosa isolates from 9 Peruvian hospitals. The 76.6% (154/201) of the isolates presented the crpP gene. Overall, 123/201 (61.2%) isolates were non-susceptible to ciprofloxacin. The prevalence of crpP-possessing P. aeruginosa in Peru is higher than in other geographical areas.

Keywords: CrpP; PMQR; TMQR; phosphorylase; quinolone-resistance.

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Conflict of interest statement

The authors declared no conflicts of interest.

References

    1. Ruiz J. Transferable mechanisms of quinolone resistance from 1998 onward. Clin Microbiol Rev. 2019;32:e00007–e00019. doi: 10.1128/CMR.00007-19. - DOI - PMC - PubMed
    1. Zubyk H.L., Wright G.D. CrpP is not a fluoroquinolone-inactivating enzyme. Antimicrob Agents Chemother. 2021;65 doi: 10.1128/AAC.00773-21. - DOI - PMC - PubMed
    1. Botelho J., Grosso F., Peixe L. ICEs are the main reservoirs of the ciprofloxacin-modifying crpP gene in Pseudomonas aeruginosa. Genes. 2020;11:889. doi: 10.3390/genes11080889. - DOI - PMC - PubMed
    1. Ortiz de la Rosa J.M., Nordmann P., Poirel L. Pathogenicity genomic island-associated CrpP-like fluoroquinolone-modifying enzymes among Pseudomonas aeruginosa clinical isolates in Europe. Antimicrob Agents Chemother. 2020;64 doi: 10.1128/AAC.00489-20. e00489-20. - DOI - PMC - PubMed
    1. Xu Y., Zhang Y., Zheng X., Yu K., Sun Y., Liao W., et al. The prevalence and functional characteristics of CrpP-like in Pseudomonas aeruginosa isolates from China. Eur J Clin Microbiol Infect Dis. 2021;40:2651–2656. doi: 10.1007/s10096-021-04287-2. - DOI - PubMed