Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2023 Feb;8(2):121-123.
doi: 10.1016/j.jacbts.2023.01.010. Epub 2023 Feb 27.

Cardiac Pericytes: Underappreciated Targets of SARS-CoV-2

Mitali Das  1 , Mina K Chung  1   2
Affiliations
Editorial

Cardiac Pericytes: Underappreciated Targets of SARS-CoV-2

Mitali Das et al. JACC Basic Transl Sci. 2023 Feb.
No abstract available

Keywords: COVID-19; SARS-CoV-2; pericytes.

PubMed Disclaimer

Conflict of interest statement

This work was funded by 810959 AHA Covid-19 Rapid Response Research Coordinating Center grant, 814633 AHA Covid-19 Rapid Response Research grant, NIH/NHLBI R01HL111314, and P01HL158502. The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

None
Graphical abstract
See this image and copyright information in PMC

Comment on

  • Human Cardiac Pericytes Are Susceptible to SARS-CoV-2 Infection.
    Brumback BD, Dmytrenko O, Robinson AN, Bailey AL, Ma P, Liu J, Hicks SC, Ng S, Li G, Zhang DM, Lipovsky CE, Lin CY, Diamond MS, Lavine KJ, Rentschler SL. Brumback BD, et al. JACC Basic Transl Sci. 2023 Feb;8(2):109-120. doi: 10.1016/j.jacbts.2022.09.001. Epub 2022 Sep 14. JACC Basic Transl Sci. 2023. PMID: 36124009 Free PMC article.

References

    1. Geevarghese A., Herman I.M. Pericyte-endothelial crosstalk: implications and opportunities for advanced cellular therapies. Transl Res. 2014;163:296–306. - PMC - PubMed
    1. Tucker N.R., Chaffin M., Bedi K.C., Jr., Papangeli I., Akkad A.D., Arduini A., et al. Myocyte-specific upregulation of ACE2 in cardiovascular disease: implications for SARS-CoV-2-mediated myocarditis. Circulation. 2020;142:708–710. - PMC - PubMed
    1. Nicin L., Abplanalp W.T., Mellentin H., Kattih B., Tombor L., John D., et al. Cell type-specific expression of the putative SARS-CoV-2 receptor ACE2 in human hearts. Eur Heart J. 2020;41:1804–1806. - PMC - PubMed
    1. McCracken I.R., Saginc G., He L., Huseynov A., Daniels A., Fletcher S., et al. Lack of evidence of ACE2 expression and replicative infection by SARSCoV-2 in human endothelial cells. Circulation. 2021;143:865–868. - PMC - PubMed
    1. Cardot-Leccia N., Hubiche T., Dellamonica J., Burel-Vandenbos F., Passeron T. Pericyte alteration sheds light on micro-vasculopathy in COVID-19 infection. Intensive Care Med. 2020;46:1777–1778. - PMC - PubMed