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Editorial
. 2022 Oct;26(10):1069-1071.
doi: 10.5005/jp-journals-10071-24336.

Anti-cytokine Therapy in Hospitalized Patients with COVID-19: The Jury is Out

Sunil Kumar Garg  1
Affiliations
Editorial

Anti-cytokine Therapy in Hospitalized Patients with COVID-19: The Jury is Out

Sunil Kumar Garg. Indian J Crit Care Med. 2022 Oct.

Abstract

How to cite this article: Garg SK. Anti-cytokine Therapy in Hospitalized Patients with COVID-19: The Jury is Out. Indian J Crit Care Med 2022;26(10):1069-1071.

Keywords: Anakinra; Anti-cytokine therapy; Anti-inflammatory therapy; Corona virus-2019; Cytokine storm; Inflammatory biomarker; Interleukin 1; Interleukin 6 receptor antagonists; Interleukin receptor antagonist; Tocilizumab.

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Conflict of interest statement

Source of support: Nil Conflict of interest: None

References

    1. Kyriazopoulou E, Huet T, Cavalli G, Gori A, Kyprianou M, Pickkers P, et al. Effect of anakinra on mortality in patients with COVID-19: A systematic review and patient-level meta-analysis. Lancet Rheumatol. 2021;3:e690–e697. doi: 10.1016/S2665-9913(21)00216-2. - DOI - PMC - PubMed
    1. Henry BM, de Oliveira MHS, Benoit S, Plebani M, Lippi G. Hematologic, biochemical, and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): A meta-analysis. Clin Chem Lab Med. 2020;58:1021–1028. doi: 10.1515/cclm-2020-0369. - DOI - PubMed
    1. The National Institutes of Health. COVID-19 treatment guidelines. Available at: https://www.covid19treatmentguidelines.nih.gov/therapies/immunomodulator... . Accessed on: 9 September 2022. - PubMed
    1. RECOVERY Collaborative Group, Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, et al. Dexamethasone in hospitalized patients with COVID-19. N Engl J Med. 2021;384(8):693–704. doi: 10.1056/NEJMoa2021436. Accessed on: 9 September 2022. - DOI - PMC - PubMed
    1. REMAP-CAP Investigators, Gordon AC, Mouncey PR, Al-Beidh F, Rowan KM, D Nicho AD, et al. Interleukin-6 receptor antagonists in critically ill patients with COVID-19. N Engl J Med. 2021;384(16):1491–1502. doi: 10.1056/NEJMoa2100433. - DOI - PMC - PubMed

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