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Case Reports
. 2023 Apr 5;69(1):51-55.
doi: 10.5387/fms.2022-22. Epub 2023 Mar 4.

Ovarian strumal carcinoid: a case report

Masaru Kanasugi  1 , Hiroshi Nishiyama  1 , Minoru Sanpei  1 , Shigeyuki Asano  2 , Tsuyoshi Honda  1
Affiliations
Case Reports

Ovarian strumal carcinoid: a case report

Masaru Kanasugi et al. Fukushima J Med Sci. .

Abstract

Background: Carcinoid tumors of the ovary are rare tumors, histopathologically classified as monodermal teratomas and somatic-type tumors arising from dermoid cysts. Their malignancy varies from borderline to malignant. Carcinoid tumors can occur in young and elderly women, and are sometimes seen in mature teratoma, struma ovarii, or mucinous cystadenoma as a nodule or tumor. Strumal carcinoid and mucinous carcinoid present as special types of carcinoid tumors of the ovary.

Case report: This report describes a 56-year-old woman who presented with a large pelvic mass on abdominal ultrasonography during a medical examination. The diameter of the pelvic tumor was approximately 11 cm and was suspected to be ovarian cancer. The values of CA125 and CEA were above their reference intervals on preoperative examination. Abdominal total hysterectomy and bilateral salpingo-oophorectomy were performed. Intraoperative frozen-section histopathology suggested a diagnosis of mucinous adenocarcinoma; therefore, partial omentectomy and pelvic lymphadenectomy were also performed. Permanent-section histopathology led to a final diagnosis of strumal carcinoid of the ovary, stage IA (FIGO 2014). Six years post-operation, the patient had no sign of recurrence.

Keywords: case report; clinical diagnosis; histopathological feature; ovarian strumal carcinoid; treatment.

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Conflict of interest statement

The authors have no conflicts of interest directly relevant to the content of this article.

Figures

Fig. 1A
Fig. 1A
CT (contrast CT)
Fig 1B.
Fig 1B.
MRI (upper: T2, lower: T1 with Gd enhancement)
Fig. 2
Fig. 2
Macroscopic finding of right ovary
Fig. 3A
Fig. 3A
Cord-like structure in strumal carcinoid (HE, ×400)
Fig. 3B
Fig. 3B
Colloids in strumal carcinoid (HE, ×400)
Fig. 3C
Fig. 3C
Mixed structures of colloids and cord-like lesios in strumal carcinoid (HE, ×200)
Fig. 4A
Fig. 4A
I nsular sequence stained with CD56 × 200
Fig. 4B
Fig. 4B
Cord like structure stained with chromogranin A (× 200)
Fig. 4C
Fig. 4C
Cord and insular sequence stained with synaptophysin (× 200)
Fig. 4D
Fig. 4D
Colloid stained with TTF 1 (× 200)
See this image and copyright information in PMC

References

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