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. 2023 Mar 7;13(3):e070810.
doi: 10.1136/bmjopen-2022-070810.

Effectiveness of spiritual interventions on psychological outcomes and quality of life among paediatric patients with cancer: a study protocol for a systematic review

Qi Liu  1 , Ka Yan Ho  2 , Katherine Ka Wai Lam  1 , Jacqueline Mei Chi Ho  1 , Winsome Lam  1 , Polly Ma  1 , Hammoda Abu-Odah  1 , Getaneh Mulualem Belay  1 , Dong-Lan Ling  1 , Shirley-Siu-Yin Ching  1 , Frances-Kam-Yuet Wong  1
Affiliations

Effectiveness of spiritual interventions on psychological outcomes and quality of life among paediatric patients with cancer: a study protocol for a systematic review

Qi Liu et al. BMJ Open. .

Abstract

Introduction: Cancer and its treatment affect children's physical, psychological and social well-being throughout the disease trajectory. Spiritual well-being is a fundamental dimension of people's overall health and is considered a source of strength to motivate patients to cope with and adapt to their disease. Appropriate spiritual interventions are important to mitigate the psychological impact of cancer on children, with an ultimate goal of improving their quality of life (QoL) throughout the treatment course. However, the overall effectiveness of spiritual interventions for paediatric patients with cancer remains unclear. This paper describes a protocol to systematically summarise the characteristics of studies related to existing spiritual interventions and synthesise their effectiveness on psychological outcomes and QoL among children with cancer.

Methods and analysis: Ten databases will be searched to identify appropriate literature: MEDLINE, the Cochrane Central Register of Controlled Trials, EMBASE, CINAHL, PsycINFO, LILACS, OpenSIGLE, the Chinese Biomedical Literature Database, the Chinese Medical Current Contents and the Chinese National Knowledge Infrastructure. All randomised controlled trials that meet our inclusion criteria will be included. The primary outcome will be QoL as evaluated by self-reported measures. The secondary outcomes will be self-reported or objectively measured psychological outcomes, including anxiety and depression. Review Manager V.5.3 will be used to synthesise the data, calculate treatment effects, perform any subgroup analyses and assess the risk of bias in included studies.

Ethical and dissemination: The results will be presented at international conferences and published in peer-reviewed journals. As no individual data will be involved in this review, ethical approval is not required.

Keywords: mental health; paediatric oncology; quality of Life.

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Conflict of interest statement

Competing interests: None declared.

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