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. 2023 Jan;6(1):19-21.
Epub 2022 Dec 22.

Biomaterials Interventions for Pelvic Organ Prolapse

Katrina M Knight  1
Affiliations

Biomaterials Interventions for Pelvic Organ Prolapse

Katrina M Knight. JPhys Mater. 2023 Jan.
No abstract available

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Figures

Figure 1:
Figure 1:
Synthetic meshes have been utilized in the treatment of pelvic floor disorders for many years. Pictured is a timeline of synthetic mesh usage in pelvic organ prolapse (POP) and stress urinary incontinence (SUI) repairs, focusing mainly on the progression of synthetic mesh in POP repairs. Reproduced with permission from K. M. Knight, B. R. Egnot, and P. A. Moalli, “Synthetic Mesh and Biologic Grafts: Properties and Biomechanics,” in Walters and Karram Urogynecology and Reconstructive Pelvic Surgery, 5th ed. M. D. Barber, C. S. Bradley, M. M. Karram, and M. D. Walters, Eds. Philadelphia, PA: Elsevier, 2021, ch. 7 pp. 93–114 [9].
Figure 2:
Figure 2:
There are three main types of biologic grafts utilized in pelvic organ prolapse repairs: autografts (derived from patient), allografts (human source excluding patient), and xenografts (animal source). Examples of each type of graft as well as the associated pros and cons are discussed. Reproduced with permission from K. M. Knight, B. R. Egnot, and P. A. Moalli, “Synthetic Mesh and Biologic Grafts: Properties and Biomechanics,” in Walters and Karram Urogynecology and Reconstructive Pelvic Surgery, 5th ed. M. D. Barber, C. S. Bradley, M. M. Karram, and M. D. Walters, Eds. Philadelphia, PA: Elsevier, 2021, ch. 7 pp. 93–114 [9].
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References

    1. Jelovsek JE, Maher C, and Barber MD, “Pelvic organ prolapse,” Lancet, vol. 369, no. 9566, pp. 1027–1038, 2007. [Online]. Available: http://www.scopus.com/inward/record.url?eid=2-s2.0-33947203965&partnerID.... - PubMed
    1. Emge LA and Durfee RB, “Pelvic organ prolapse: four thousand years of treatment,” Clinical Obstetrics and Gynecology, vol. 9, no. 4, pp. 997–1032, 1966. [Online]. Available: http://www.scopus.com/inward/record.url?eid=2-s2.0-0013991920&partnerID=.... - PubMed
    1. Barber MD et al., “Comparison of 2 transvaginal surgical approaches and perioperative behavioral therapy for apical vaginal prolapse: The OPTIMAL randomized trial,” JAMA - Journal of the American Medical Association, vol. 311, no. 10, pp. 1023–1034, 2014, doi: 10.1001/jama.2014.1719. - DOI - PMC - PubMed
    1. Jelovsek JE et al., “Effect of uterosacral ligament suspension vs sacrospinous ligament fixation with or without perioperative behavioral therapy for pelvic organ vaginal prolapse on surgical outcomes and prolapse symptoms at 5 years in the OPTIMAL randomized clinical trial,” JAMA - Journal of the American Medical Association, Article vol. 319, no. 15, pp. 1554–1565, 2018, doi: 10.1001/jama.2018.2827. - DOI - PMC - PubMed
    1. FDA. (2011). Surgical Mesh for Treatment of Women with Pelvic Organ Prolapse and Stress Urinary Incontinence: FDA Executive Summary [Online] Available: http://www.fda.gov/downloads/UCM270402.pdf

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