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Case Reports
. 2023 Mar 30;388(13):1246-1247.
doi: 10.1056/NEJMc2214921. Epub 2023 Mar 8.

An Mpox-Related Death in the United States

Jemma Alarcón  1 , Moon Kim  2 , Dawn Terashita  2 , Kusha Davar  3 , Jacob M Garrigues  2 , Jack P Guccione  4 , Mark G Evans  5 , Peera Hemarajata  2 , Noah Wald-Dickler  3 , Paul Holtom  3 , Rodrigo Garcia Tome  3 , Lovelyn Anyanwu  2 , Naman K Shah  2 , Matthew Miller  4 , Todd Smith  6 , Audrey Matheny  6 , Whitni Davidson  6 , Christina L Hutson  6 , Jonathan Lucas  4 , Odey C Ukpo  4 , Nicole M Green  2 , Sharon E Balter  2
Affiliations
Case Reports

An Mpox-Related Death in the United States

Jemma Alarcón et al. N Engl J Med. .
No abstract available

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Figures

Figure 1.
Figure 1.. Lesions and Cytopathic Effects.
Photographs show lesions on the left hand (Panel A) and in the esophagus (Panel B). Histologic examination of the esophageal mucosa (Panel C; hematoxylin and eosin stain) shows an epithelial cell with an intracellular eosinophilic inclusion that is consistent with a Guarnieri body (arrow).
See this image and copyright information in PMC

References

    1. Centers for Disease Control and Prevention. Mpox: 2022 outbreak cases and data. February 15, 2023. (https://www.cdc.gov/poxvirus/monkeypox/response/2022/index.html).
    1. Curran KG, Eberly K, Russell OO, et al. HIV and sexually transmitted infections among persons with monkeypox — eight U.S. jurisdictions, May 17–July 22, 2022. MMWR Morb Mortal Wkly Rep 2022;71:1141–7. - PMC - PubMed
    1. Duraffour S, Lorenzo MM, Zöller G, et al. ST-246 is a key antiviral to inhibit the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping. J Antimicrob Che-mother 2015;70:1367–80. - PMC - PubMed
    1. Food and Drug Administration. FDA Mpox response. February 22, 2023. (https://www.fda.gov/emergency-preparedness-and-response/mcm-issues/fda-m...).
    1. Centers for Disease Control and Prevention. Update on managing monkeypox in patients receiving therapeutics. November 17, 2022. (https://emergency.cdc.gov/han/2022/han00481.asp).