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Comment
. 2023 Mar 7;35(3):381-383.
doi: 10.1016/j.cmet.2023.02.011.

Unanticipated metabolic plasticity in response to chronic hypoxia

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Unanticipated metabolic plasticity in response to chronic hypoxia

Ioanna Papandreou et al. Cell Metab. .
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Abstract

In this issue of Cell Metabolism, Midha et al. investigate the metabolic changes in mice after exposure to reduced oxygen tension for an acute or chronic duration. Their organ-specific findings may help explain physiological observations in humans living at high altitude but raise additional questions concerning pathological hypoxia after vascular damage or in cancer.

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Declaration of interests The authors declare no competing interests.

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