Unanticipated metabolic plasticity in response to chronic hypoxia
- PMID: 36889278
- DOI: 10.1016/j.cmet.2023.02.011
Unanticipated metabolic plasticity in response to chronic hypoxia
Abstract
In this issue of Cell Metabolism, Midha et al. investigate the metabolic changes in mice after exposure to reduced oxygen tension for an acute or chronic duration. Their organ-specific findings may help explain physiological observations in humans living at high altitude but raise additional questions concerning pathological hypoxia after vascular damage or in cancer.
Copyright © 2023 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Organ-specific fuel rewiring in acute and chronic hypoxia redistributes glucose and fatty acid metabolism.Cell Metab. 2023 Mar 7;35(3):504-516.e5. doi: 10.1016/j.cmet.2023.02.007. Cell Metab. 2023. PMID: 36889284 Free PMC article.
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