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Case Reports
. 2023 Feb 4;15(2):e34625.
doi: 10.7759/cureus.34625. eCollection 2023 Feb.

Rhabdomyolysis-Induced Acute Kidney Injury (AKI) in a Young Bodybuilder: A Case Report

Jamsheer Parammal Alikutty  1 , Anoop Raj  2 , Sirajudheen K Soofi  2 , Amer A Alkhateeb  2 , Ahmed A Soliman  2 , Fawwaz R Al Amiri  2 , Ahmad A Abujaber  2 , Mohamed Zuhail K Peediyakkal  1 , Mohamad Khatib  1 , Abdulqadir J Nashwan  2
Affiliations
Case Reports

Rhabdomyolysis-Induced Acute Kidney Injury (AKI) in a Young Bodybuilder: A Case Report

Jamsheer Parammal Alikutty et al. Cureus. .

Abstract

Acute kidney injury (AKI) is a serious medical condition that can have many causes, including rhabdomyolysis. Rhabdomyolysis is the breakdown of muscle tissue that can lead to the release of muscle fiber contents into the bloodstream. This can cause serious damage to the kidneys, leading to AKI. In this case, a young bodybuilder was diagnosed with rhabdomyolysis induced by AKI after consuming Ibuprofen for a casual fever. The etiology of AKI in rhabdomyolysis is complex, with multiple factors contributing to the development of the condition. These include muscle trauma, dehydration, infection, and drug toxicity. In this case, Ibuprofen may have contributed to the development of AKI, as it can cause kidney damage when taken in large doses. Additionally, the bodybuilder's physical activity may have contributed to the development of rhabdomyolysis, as intense exercise can cause muscle damage. Treatment for AKI in rhabdomyolysis patients typically involves aggressive fluid resuscitation, electrolyte replacement, and dialysis if necessary. Additionally, the underlying cause of the rhabdomyolysis must be identified and treated. In this case, the patient should be monitored closely for any signs of kidney damage, and the Ibuprofen should be discontinued. In conclusion, this is a case of a relatively common presentation with uncommon circumstances. It is crucial to have a heightened understanding of the likelihood of AKI in patients with rhabdomyolysis and the impact of drug toxicity in exacerbating the condition. Early diagnosis and treatment are essential for the successful management of AKI.

Keywords: acute kidney injury; bodybuilding; ibuprofen; nonsteroidal anti-inflammatory drugs; rhabdomyolysis.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Ultrasound of the abdomen and pelvis shows both kidneys appear normal in shape, size, and echogenicity.
Figure 2
Figure 2. Urea trends.
Figure 3
Figure 3. Creatinine trends.
Figure 4
Figure 4. Creatine kinase trends.
Figure 5
Figure 5. Myoglobin trends.
See this image and copyright information in PMC

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