Reply to "Type I IFN Signature in NOTCH1-Related Leukoencephalopathy"

Dorit Verhoeven^{1

2}, Samantha A M Tromp^{1

2}, Marjo S van der Knaap^{3

4

5}, Taco W Kuijpers^{1

2}

Affiliations

¹ Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children's Hospital, Amsterdam University Medical Centers, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
² Department of Experimental Immunology, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
³ Department of Child Neurology, Emma Children's Hospital, Amsterdam University Medical Centers, VU University Amsterdam and Amsterdam Neuroscience, Amsterdam, The Netherlands.
⁴ Amsterdam Leukodystrophy Center, Emma Children's Hospital, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
⁵ Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, VU University, Amsterdam, The Netherlands.

Comment

Dorit Verhoeven et al. Ann Neurol. 2023 May.

. 2023 May;93(5):1043-1045.

doi: 10.1002/ana.26629. Epub 2023 Mar 20.

Dorit Verhoeven^{1

2}, Samantha A M Tromp^{1

2}, Marjo S van der Knaap^{3

4

5}, Taco W Kuijpers^{1

2}

¹ Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children's Hospital, Amsterdam University Medical Centers, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
² Department of Experimental Immunology, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
³ Department of Child Neurology, Emma Children's Hospital, Amsterdam University Medical Centers, VU University Amsterdam and Amsterdam Neuroscience, Amsterdam, The Netherlands.
⁴ Amsterdam Leukodystrophy Center, Emma Children's Hospital, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
⁵ Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, VU University, Amsterdam, The Netherlands.

No abstract available

Comment on

Heterozygous NOTCH1 Variants Cause CNS Immune Activation and Microangiopathy.
Helman G, Zarekiani P, Tromp SAM, Andrews A, Botto LD, Bonkowsky JL, Chassevent A, Giorgio E, Pippucci T, Wei S, Smith-Hicks C, Vaula G, Willemsen MAAP, Schimmel M, Vollert K, Shimizu F, Kanda T, Lynch M, Roscioli T, Taft RJ, Simons C, Bugiani M, Kuijpers TW, van der Knaap MS. Helman G, et al. Ann Neurol. 2022 Nov;92(5):895-901. doi: 10.1002/ana.26477. Epub 2022 Aug 20. Ann Neurol. 2022. PMID: 35947102
Type I Interferon Signature in NOTCH1-Related Leukoencephalopathy.
Nicita F, Travaglini L, Matteo V, Aiello C, Longo D, Insalaco A, Bertini E, Prencipe G. Nicita F, et al. Ann Neurol. 2023 May;93(5):1041-1043. doi: 10.1002/ana.26631. Epub 2023 Mar 21. Ann Neurol. 2023. PMID: 36892079 No abstract available.