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. 2023 Dec;42(1):2187630.
doi: 10.1080/10641955.2023.2187630.

Increased risk of early-onset preeclampsia in pregnant women with COVID-19

Niraj N Mahajan  1 , Shweta Kesarwani  1 , Padmaja Kumbhar  1 , Periyasamy Kuppusamy  2 , Madhura Pophalkar  1 , Pratiksha Thamke  1 , Ruchi Asawa  1 , Saumya Sharan  1 , Smita D Mahale  3 , Rahul K Gajbhiye  2
Affiliations
Free article

Increased risk of early-onset preeclampsia in pregnant women with COVID-19

Niraj N Mahajan et al. Hypertens Pregnancy. 2023 Dec.
Free article

Abstract

Objective: To estimate incidence, risk of early and late-onset preeclampsia (PE) and understand their relationship with severity of COVID-19.

Methods: Pregnant women with COVID-19 (n = 1929) were enrolled from 1 April 2020 to 24 February 2022. Primary outcome measure was incidence and risk of early onset PE in women with COVID-19.

Results: The incidence of early and late-onset PE was 11.4% and 5.6%. Moderate to severe COVID-19 was associated with eight times higher risk of early onset PE [aOR = 8.13 (1.56-42.46), p = 0.0129] compared to asymptomatic group.

Conclusions: Risk of early onset PE was higher in pregnant women with symptomatic COVID-19 as compared to asymptomatic women.

Keywords: COVID-19; SARS-CoV-2 infection, second wave, third wave; early onset preeclampsia; first wave, late-onset preeclampsia.

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