doi: 10.1016/j.atherosclerosis.2023.02.007.
Epub 2023 Feb 23.
Evaluation of lipoprotein(a) in the prevention and management of atherosclerotic cardiovascular disease: A survey among the Lipid Clinics Network
Collaborators,
Affiliations
Collaborators
-
Lipid Clinics Network Group:
Alaa Abdelrazik 8 , Alberto Mello E Silva 9 , Alexander Vonbank 10 , Alexandros D Tselepis 11 , Alper Sonmez 12 , Angelina Passaro 13 , Anja Vogt 14 , Ann Mertens 15 , Ann Verhaegen 16 , Arman S Postadzhiyan 17 , Bahadir Kirilmaz 18 , Baris Gungor 19 , Berit S Hedegaard 20 , Bertrand Cariou 21 , Britta Otte 22 , Buğra Özkan 23 , Christ Berge 24 , Christoph F Ebenbichler 25 , Christoph J Binder 26 , Christoph Olivier 27 , Conrad Azzopardi 28 , Cristina Soler 29 , Dan Gaita 30 , Daniel Weghuber 31 , Dilek Ural 32 , Diogo Cruz 33 , Dragos Vinereanu 34 , Elena D Pencu 35 , Emil Hagström 36 , Erik B Schmidt 20 , Erik S Stroes 37 , Evangelos Liberopoulos 38 , Fabian Demeure 39 , Fabio Fimiani 40 , Fabio Pellegatta 41 , Fahri Bayram 42 , Finn L Henriksen 43 , Florian Höllerl 44 , Francesco Cipollone 45 , Francisco Araújo 46 , Franck Boccara 47 , François Paillard 48 , Gabor Simonyi 49 , Gabriella Iannuzzo 50 , Giuseppe Mandraffino 51 , Graham Bayly 52 , Gustavs Latkovskis 53 , György Paragh 54 , Hana Rosolova 55 , Handrean Soran 56 , Helle Kanstrup 57 , Hermann Toplak 58 , Hülya Çiçekçioğlu 59 , Inanc Artac 60 , Ioanna Gouni-Berthold 61 , Irfan V Duzen 62 , Isabel M Palma 63 , Istvan Reiber 64 , Iveta Dzivite-Krisane 65 , Jeanine E Roeters VAN Lennep 66 , J Balligand Jean-Luc 67 , Joao C Porto 68 , João S Duarte 69 , Johan DE Sutter 70 , José López-Miranda 71 , Jose M Mostaza 72 , Jurgita Plisiene 73 , Kadir U Mert 74 , Kirsten B Holven 75 , Kjetil Retterstøl 76 , Kristian K Thomsen 77 , Lale Tokgozoglu 78 , Laszlo Bajnok 79 , Lia E Bang 80 , Liliana Grigore 81 , Lluís Masana 82 , Loukianos S Rallidis 83 , Maciej Banach 84 , Małgorzata Waluś-Miarka 85 , Manuel Castro Cabezas 86 , Marcello Arca 87 , Margus Viigimaa 88 , Martin P Bogsrud 89 , Matej Mlinarič 90 , Matteo Pirro 91 , Maurizio Averna 92 , Meral Kayikcioglu 93 , Merete Heitmann 94 , Mette Mouridsen 95 , Michal Vrablik 96 , Michel Farnier 97 , Michel R Langlois 98 , Milad Khedr 99 , Muge Ildizli Demirbas 100 , Myra Tilney 101 , Nadia Citroni 102 , Niels P Riksen 103 , Nikolay M Runev 104 , Nora Kupstyte-Kristapone 105 , Olena Mitchenko 106 , Oliver Weingärtner 107 , Oner Ozdogan 108 , Ovidio Muñiz-Grijalvo 109 , Ozcan Basaran 110 , Pankaj Gupta 111 , Paolo Parini 112 , Patrizia Suppressa 113 , Paul Downie 114 , Pavel Jesina 115 , Pavel Kraml 116 , Pawel Burchardt 117 , Pedro Valdivielso 118 , Pedro Von Hafe 119 , Peter Fasching 120 , Philippe Moulin 121 , Quitéria Rato 9 , Reinhold Innerhofer 122 , Renata Cífková 123 , Rene Valero 124 , Roberto Scicali 125 , Robin Urbánek 126 , Roma Kavaliauskiene 127 , Roman Cibulka 128 , Sabina Zambon 129 , Sergio D'Addato 130 , Stanislav Zemek 131 , Stefano Romeo 132 , Stephanie Könemann 133 , Susanne Greber-Platzer 134 , Thomas Stulnig 135 , Thomas Muhr 136 , Tina Z Khan 137 , Tomas Freiberger 138 , Tomáš Šálek 139 , Tomas Vasylius 140 , Ulrich Laufs 141 , Ulrike Schatz 142 , Urh Groselj 143 , Victoria Marco-Benedi 144 , Vincent Maher 145 , Vladimír Blaha 146 , Vladimir Soska 147 , Volker Jj Schettler 148 , Wolfgang Reinhardt 149 , Xavier Pintó 150 , Yoto Yotov 151 , Zaneta Petrulioniene 152 , Željko Reiner 153
Affiliations
- 1 IRCCS MultiMedica, Sesto San Giovanni, MI, Italy; Epidemiology and Preventive Pharmacology Service (SEFAP), Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy. Electronic address: alberico.catapano@multimedica.it.
- 2 Department of Cardiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
- 3 Department of Preventive Cardiology and Lipidology, Medical University of Lodz, Lodz, Poland; Cardiovascular Research Centre, University of Zielona Gora, Gora, Poland.
- 4 SISA Foundation, Milan, Italy.
- 5 Epidemiology and Preventive Pharmacology Service (SEFAP), Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
- 6 IRCCS MultiMedica, Sesto San Giovanni, MI, Italy; Epidemiology and Preventive Pharmacology Service (SEFAP), Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
- 7 Imperial Centre for Cardiovascular Disease Prevention, Department of Primary Care and Public Health, Imperial College, London, UK.
- 8 University Hospital of North Midland, United Kingdom.
- 9 Sociedade Portuguesa de Aterosclerose, Portugal.
- 10 VIVIT Institute, Austria.
- 11 Dept of Chemistry, Atherothrombosis Research Center, University of Ioannina, Greece.
- 12 Department of Endocrinology and Metabolism, Ankara Guven Hospital, Turkey.
- 13 Department of Translational Medicine, University of Ferrara & Center for the Study and Treatment of Metabolic Diseases, Atherosclerosis, and Clinical Nutrition, University Hospital of Ferrara Arcispedale Sant'Anna, Italy.
- 14 Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Germany.
- 15 Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
- 16 Antwerp University Hospital, Belgium.
- 17 Medical University of Sofia, Saint Anna University Hospital, Departement of Cardiology, Bulgaria.
- 18 Canakkale Onsekiz Mart University, Medical Faculty Cardiology Dept, Turkey.
- 19 University of Health Sciences Dr. Siyami Ersek Hospital, Turkey.
- 20 Aalborg University, Denmark.
- 21 Nantes Université, CHU NANTES, CNRS, INSERM, l'institut du thorax, Nantes, France.
- 22 Universitätsklinikum Münster, Lipidambulanz, Germany.
- 23 Mersin University, Turkey.
- 24 Dept. of Cardiology, Haukeland, Unversity Hopsital, Norway.
- 25 Department for Internal Medicine I, Medical University Innsbruck, Austria.
- 26 Medical University of Vienna, Austria.
- 27 Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Germany.
- 28 Mater Dei Hospital, Malta.
- 29 Lipid Unit, Hospital de Sta Caterina, Spain.
- 30 Universitatea de Medicina si Farmacie Victor Babes din Timisoara & Clinica de Cardiologie, Institutul de Boli Cardiovasculare Timisoara, Romania.
- 31 Department of Pediatrics, Paracelsus Medical University, Austria.
- 32 Koç University School of Medicine Department of Cardiology, Turkey.
- 33 Hospital de Cascais - Dr.José de Almeida, Portugal.
- 34 University of Medicine and Pharmacy "Carol Davila", University and Emergency Hospital, Bucharest, Romania.
- 35 Grand Hôpital de Charleroi GHDC, Belgium.
- 36 Dept of Medical sciences, Uppsala University, Sweden.
- 37 Dept of Vascular Medicine, AmsterdamUMC, the Netherlands.
- 38 1th Department of Propedeutic Medicine, School of Medicine, National and Kapodistrian University of Athens, General Hospital of Athens Laiko, Greece.
- 39 CHU UCL Namur - Site Godinne, Belgium.
- 40 Azienda Ospedaliera di Rilievo Nazionale AORN Dei Colli, "V.Monaldi", Unit of Inherited and Rare Cardiovascular Diseases, Italy.
- 41 Center for the Study of Atherosclerosis, Bassini Hospital, Cinisello Balsamo, Italy.
- 42 Erciyes University, Turkey.
- 43 Department of Cardiology Odense University Hospital, Denmark.
- 44 1th Medical Department, Landstrasse Clinic, Vienna Health Association, Austria.
- 45 Clinica Medica Institute of "SS. Annunziata" Hospital, Department of Medicine and Aging Sciences, "G. d'Annunzio" University, Italy.
- 46 Hospital Lusíadas, Portugal.
- 47 Sorbonne Université, Groupe de Recherche Clinique Number 22, C2MV-Complications Cardiovasculaires et Métaboliques Chez les Patients Vivant avec le Virus de l'Immunodéficience Humaine, Institut National de la Santé et de la Recherche Médicale Unité Mixte de Recherche S 938, Centre de Recherche Saint-Antoine, Institut Hospital Universitaire de Cardio-métabolisme et Nutrition Cardiologie, Hôpital Saint Antoine Assistance Publique-Hôpitaux de Paris, Paris, France.
- 48 Cardiologie et Centre Clinico-Biologique des Lipides et Athérosclérose, CHU Rennes, France.
- 49 DBC St. Imre University Teaching Hospital, Metabolic Center, Lipid Center, Hungary.
- 50 Department of Clinical Medicine and Surgery, University of Naples Federico II, Italy.
- 51 Department of Clinical and Experimental Medicine - Lipid Center, University of Messina, Italy.
- 52 Dept Clinical Biochemistry, University Hospitals Bristol, United Kingdom.
- 53 Institute of Cardiology and Regenerative Medicine, University of Latvia & Latvian Center of Cardiology, Pauls Stradins Clinical University Hospital & Faculty of Medicine, University of Latvia, Latvia.
- 54 Division of Metabolic Disorders, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
- 55 Charles University Prague Medical Hospital in Pilsen, Czech Republic.
- 56 Central Manchester University Hospital NHS Foundation Trust, United Kingdom.
- 57 Department of Cardiology, Aarhus University Hospital, Denmark.
- 58 Department of Medicine, Division of Endocrinology and Diabetology, Medical University Graz, Austria.
- 59 Ankara Bilkent City Hospital, Turkey.
- 60 Department of Cardiology, Kafkas University Hospital, Faculty of Medicine, Turkey.
- 61 Center for Endocrinology, Diabetes and Preventive Medicine, University of Cologne, Faculty of Medicine and University Hospital Cologne, Germany.
- 62 Gaziantep University, Faculty of Medicine, Cardiology Department, Turkey.
- 63 CHUPORTO - Centro Hospitalar Universitário do Porto, Portugal.
- 64 Szent Gyorgy University Teaching Hospital of Fejer County, Hungary.
- 65 Children's University Hospital, Latvia.
- 66 Department of Internal Medicine, Erasmus MC University Medical Center, the Netherlands.
- 67 Institut de Recherche Expérimentale et Clinique, Universite Catholique de Louvain, Bruxelles, Belgium.
- 68 CHUC, Portugal.
- 69 Hospital Egas Moniz, Lisboa, Portugal.
- 70 AZ Maria Middelares Hospital Gent, Belgium.
- 71 Lipid and Arteriosclerosis Unit. Department of Internal Medicine, Hospital Universitario Reina Sofia, IMIBIC, University of Cordoba. CiberOBN, Spain.
- 72 Hospital La Paz-Carlos III, Spain.
- 73 Lithuanian University of Health sciences, Lithuania.
- 74 Eski?ehir Osmangazi University, Faculty of Medicine, Department of Cardiology, Turkey.
- 75 Department of Nutrition, University of Oslo and National Advisory Unit on FH, Oslo University Hospital, Norway.
- 76 The Lipid Clinic, Oslo University Hospital and Department of Nutrition, University of Oslo, Norway.
- 77 University Hospital of South Denmark, Esbjerg, Denmark.
- 78 Hacettepe University, Turkey.
- 79 1th Department of Medicine, Medical School, University of Pecs, Hungary.
- 80 Copenhagen University Hospital, Denmark.
- 81 IRCCS Multimedica, Italy.
- 82 Hospital Universitari Sant Joan, Universitat Rovira i Virgili, CIBERDEM, Reus, Spain.
- 83 University General Hospital Attikon, Greece.
- 84 Department of Preventive Cardiology and Lipidology, Medical University of Lodz, Poland.
- 85 Jagiellonian University Medical College, Dept. of Metabolic Diseases and Diabetology, Poland.
- 86 Franciscus Gasthuis & Vlietland, Rotterdam, the Netherlands.
- 87 Sapienza University of Rome, Italy.
- 88 North Estonia Medical Centre, Tallinn University of Technology, Estonia.
- 89 Unit for Cardiac and Cardiovascular Genetics, Oslo University Hospital, Norway.
- 90 Department of Endocrinology, Diabetes and Metabolism, University Children's Hospital, University Medical Centre Ljubljana, Slovenia.
- 91 Section of Internal Medicine, Angiology and Arteriosclerosis Diseases, Italy.
- 92 Department PROMISE-University of Palermo & Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Palermo, Italy.
- 93 Ege University Medical School Department of Cardiology, Turkey.
- 94 Bispebjerg-Frederiksberg University Hospital, Denmark.
- 95 Department of Cardiology, Herlev and Gentofte Hospital, University of Copenhagen, Denmark.
- 96 3rd Department of Internal Medicine, General University Hospital and 1st Medical Faculty, Charles University, Prague, Czech Republic.
- 97 PEC2, University of Bourgogne Franche-Comté, France.
- 98 Dept. Laboratory Medicine, AZ St.Jan Hospital, Belgium.
- 99 Department of Clinical Biochemistry and Metabolic Medicine, Royal Liverpool University Hospital, United Kingdom.
- 100 Kartal Kosuyolu Research and Training Hospital, Turkey.
- 101 Lipid Clinic, Mater Dei Hospital & Dept of Medicine, University of Malta Medical School, Malta.
- 102 Internal Medicine, APSS Trento Hospital, Italy.
- 103 Dept. of Internal Medicine, Radboud University Medical Center, the Netherlands.
- 104 UMHAT Alexandrovska, Bulgaria.
- 105 Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Lithuania.
- 106 NSC "Institute of Cardiology, Clinical and Regenerative Medicine of the NAMS of Ukraine", Ukraine.
- 107 Universitätsklinikum Jena, Department of Internal Medicine I, Germany.
- 108 University of Health Sciences, Izmir Faculty of Medicine, Tepecik Training and Research Hospital, Department of Cardiology, Turkey.
- 109 Hospital Virgen del Rocío, Spain.
- 110 Mugla Sitki Kocman University, Faculty of Medicine, Cardiology Department, Turkey.
- 111 University Hospitals of Leicester, United Kingdom.
- 112 Cardio Metabolic Unit, Karolinska Institutet, And Theme Inflammation and Ageing, Karolinska University Hospital Huddinge, Sweden.
- 113 Department of Internal Medicine and Rare disease Centre "C. Frugoni" University Hospital of Bari, Bari, Italy.
- 114 Salisbury NHS Foundation trust, United Kingdom.
- 115 Metabolic Center General University Hospital, Czech Republic.
- 116 Dept.of Internal Medicine, Third Faculty of Medicine, Charles University and Královské Vinohrady University Hospital Prague, Czech Republic.
- 117 Department of Cardiology, Cardiovascular Unit, J. Stru? Hospital, Poznań & Department of Hypertension, Angiology and Internal Medicine, Poznan University of Medical Sciences, Poznań, Poland.
- 118 Hospital VIRGEN DE LA VICTORIA, Spain.
- 119 Instituto Cuf, Portugal.
- 120 5th Med. Dept, Clinic Ottakring, Austria.
- 121 Hospices Civils de Lyon, INSERM, Université Lyon1, Hôpital Louis Pradel, Fédération d'endocrinologie, France.
- 122 Medical University Vienna, Austria.
- 123 Center for Cardiovascular Prevention, Charles University in Prague, First Faculty of Medicine and Thomayer University Hospital, Prague, Czech Republic.
- 124 Aix Marseille Univ, APHM, INSERM, INRAE, C2VN, University Hospital La Conception, Department of Nutrition, Metabolic Diseases and Endocrinology, France.
- 125 Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
- 126 Internal Medicine, Obezita-Ormiga s.r.o, Czech Republic.
- 127 Klaip?da Seamen's Hospital, Lithuania.
- 128 Department of Paramedic science, Medical diagnostics studies and Public Health, Faculty of Health Care Studies, University of West Bohemia, Czech Republic.
- 129 Department of Medicine - DIMED, University of Padova, Italy.
- 130 University of Bologna, IRCCS S.Orsola Bologna, Italy.
- 131 Lipidova ambulance, Czech Republic.
- 132 Gothenburg University, Sweden.
- 133 Department of Internal Medicine B, University Medicine Greifswald, DZHK, Germany.
- 134 Clinical Division of Pediatric Pulmonology, Allergology and Endocrinology, Department of Pediatrics and Adolescent Medicine, Medical University, Vienna, Austria.
- 135 Clinical Division of Endocrinology and Metabolism, Department of Medicine III, Medical University Vienna & Third Medical Department and Karl Landsteiner Institute for Metabolic Diseases and Nephrology, Clinic Hietzing, Vienna, Austria.
- 136 Dept of Cardiology, Linköping University Hospital, Sweden.
- 137 Consultant Cardiologist, Royal Brompton and Harefield Hospitals Part of Guy's and St Thomas' NHS Foundation Trust, United Kingdom.
- 138 Centre of Cardiovascular Surgery and Transplantation, Brno & Medical Faculty, Masaryk University, Brno, Czech Republic.
- 139 Metabolic Clinic, Tomas Bata Hospital, Zlín, Czech Republic.
- 140 Republican Panevezys Hospital, Dep. of Cardiology, Lithuania.
- 141 Klinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany.
- 142 University Hospital Carl Gustav Carus Dresden at the Technical University Dresden, Department of Internal Medicine III, Germany.
- 143 UMC - University Children's Hospital Ljubljana, University of Ljubljana, Faculty of Medicine, Slovenia.
- 144 Hospital Universitario Miguel Servet, IISA, CIBERCV, Spain.
- 145 Advanced Lipid Management and Research ALMAR Centre, Tallaght University Hospital, Ireland.
- 146 University Hospital Hradec Králové and Charles University, Faculty of Medicine in Hradec Králové, 3rd Department of Internal Medicine - Metabolism and Gerontology, Czech Republic.
- 147 Department of Clinical Biochemistry, St. Anne's University Hospital Brno, 2nd Clinic of Internal Medicine, Faculty of Medicine, Masaryk University Brno, Czech Republic.
- 148 Centre of Nephrology Göttingen, Germany.
- 149 SUS Malmoe, Sweden.
- 150 Hospital Universitari de Bellvitge-Idibell-UB-CiberObn, Spain.
- 151 Second Cardiology Clinic, University Hospital Sv. Marina, Medical University of Varna, Bulgaria.
- 152 Vilnius University Medical Faculty, Vilnius University Hospital Santaros klinikos, Lithuania.
- 153 Department for Metabolic Diseases, University Hospital Center Zagreb, Croatia.
- PMID: 36894469
- DOI: 10.1016/j.atherosclerosis.2023.02.007
Item in Clipboard
Evaluation of lipoprotein(a) in the prevention and management of atherosclerotic cardiovascular disease: A survey among the Lipid Clinics Network
Alberico L Catapano et al.
Atherosclerosis.
2023 Apr.
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Format
doi: 10.1016/j.atherosclerosis.2023.02.007.
Epub 2023 Feb 23.
Authors
Collaborators
-
Lipid Clinics Network Group:
Alaa Abdelrazik 8 , Alberto Mello E Silva 9 , Alexander Vonbank 10 , Alexandros D Tselepis 11 , Alper Sonmez 12 , Angelina Passaro 13 , Anja Vogt 14 , Ann Mertens 15 , Ann Verhaegen 16 , Arman S Postadzhiyan 17 , Bahadir Kirilmaz 18 , Baris Gungor 19 , Berit S Hedegaard 20 , Bertrand Cariou 21 , Britta Otte 22 , Buğra Özkan 23 , Christ Berge 24 , Christoph F Ebenbichler 25 , Christoph J Binder 26 , Christoph Olivier 27 , Conrad Azzopardi 28 , Cristina Soler 29 , Dan Gaita 30 , Daniel Weghuber 31 , Dilek Ural 32 , Diogo Cruz 33 , Dragos Vinereanu 34 , Elena D Pencu 35 , Emil Hagström 36 , Erik B Schmidt 20 , Erik S Stroes 37 , Evangelos Liberopoulos 38 , Fabian Demeure 39 , Fabio Fimiani 40 , Fabio Pellegatta 41 , Fahri Bayram 42 , Finn L Henriksen 43 , Florian Höllerl 44 , Francesco Cipollone 45 , Francisco Araújo 46 , Franck Boccara 47 , François Paillard 48 , Gabor Simonyi 49 , Gabriella Iannuzzo 50 , Giuseppe Mandraffino 51 , Graham Bayly 52 , Gustavs Latkovskis 53 , György Paragh 54 , Hana Rosolova 55 , Handrean Soran 56 , Helle Kanstrup 57 , Hermann Toplak 58 , Hülya Çiçekçioğlu 59 , Inanc Artac 60 , Ioanna Gouni-Berthold 61 , Irfan V Duzen 62 , Isabel M Palma 63 , Istvan Reiber 64 , Iveta Dzivite-Krisane 65 , Jeanine E Roeters VAN Lennep 66 , J Balligand Jean-Luc 67 , Joao C Porto 68 , João S Duarte 69 , Johan DE Sutter 70 , José López-Miranda 71 , Jose M Mostaza 72 , Jurgita Plisiene 73 , Kadir U Mert 74 , Kirsten B Holven 75 , Kjetil Retterstøl 76 , Kristian K Thomsen 77 , Lale Tokgozoglu 78 , Laszlo Bajnok 79 , Lia E Bang 80 , Liliana Grigore 81 , Lluís Masana 82 , Loukianos S Rallidis 83 , Maciej Banach 84 , Małgorzata Waluś-Miarka 85 , Manuel Castro Cabezas 86 , Marcello Arca 87 , Margus Viigimaa 88 , Martin P Bogsrud 89 , Matej Mlinarič 90 , Matteo Pirro 91 , Maurizio Averna 92 , Meral Kayikcioglu 93 , Merete Heitmann 94 , Mette Mouridsen 95 , Michal Vrablik 96 , Michel Farnier 97 , Michel R Langlois 98 , Milad Khedr 99 , Muge Ildizli Demirbas 100 , Myra Tilney 101 , Nadia Citroni 102 , Niels P Riksen 103 , Nikolay M Runev 104 , Nora Kupstyte-Kristapone 105 , Olena Mitchenko 106 , Oliver Weingärtner 107 , Oner Ozdogan 108 , Ovidio Muñiz-Grijalvo 109 , Ozcan Basaran 110 , Pankaj Gupta 111 , Paolo Parini 112 , Patrizia Suppressa 113 , Paul Downie 114 , Pavel Jesina 115 , Pavel Kraml 116 , Pawel Burchardt 117 , Pedro Valdivielso 118 , Pedro Von Hafe 119 , Peter Fasching 120 , Philippe Moulin 121 , Quitéria Rato 9 , Reinhold Innerhofer 122 , Renata Cífková 123 , Rene Valero 124 , Roberto Scicali 125 , Robin Urbánek 126 , Roma Kavaliauskiene 127 , Roman Cibulka 128 , Sabina Zambon 129 , Sergio D'Addato 130 , Stanislav Zemek 131 , Stefano Romeo 132 , Stephanie Könemann 133 , Susanne Greber-Platzer 134 , Thomas Stulnig 135 , Thomas Muhr 136 , Tina Z Khan 137 , Tomas Freiberger 138 , Tomáš Šálek 139 , Tomas Vasylius 140 , Ulrich Laufs 141 , Ulrike Schatz 142 , Urh Groselj 143 , Victoria Marco-Benedi 144 , Vincent Maher 145 , Vladimír Blaha 146 , Vladimir Soska 147 , Volker Jj Schettler 148 , Wolfgang Reinhardt 149 , Xavier Pintó 150 , Yoto Yotov 151 , Zaneta Petrulioniene 152 , Željko Reiner 153
Affiliations
- 1 IRCCS MultiMedica, Sesto San Giovanni, MI, Italy; Epidemiology and Preventive Pharmacology Service (SEFAP), Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy. Electronic address: alberico.catapano@multimedica.it.
- 2 Department of Cardiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
- 3 Department of Preventive Cardiology and Lipidology, Medical University of Lodz, Lodz, Poland; Cardiovascular Research Centre, University of Zielona Gora, Gora, Poland.
- 4 SISA Foundation, Milan, Italy.
- 5 Epidemiology and Preventive Pharmacology Service (SEFAP), Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
- 6 IRCCS MultiMedica, Sesto San Giovanni, MI, Italy; Epidemiology and Preventive Pharmacology Service (SEFAP), Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
- 7 Imperial Centre for Cardiovascular Disease Prevention, Department of Primary Care and Public Health, Imperial College, London, UK.
- 8 University Hospital of North Midland, United Kingdom.
- 9 Sociedade Portuguesa de Aterosclerose, Portugal.
- 10 VIVIT Institute, Austria.
- 11 Dept of Chemistry, Atherothrombosis Research Center, University of Ioannina, Greece.
- 12 Department of Endocrinology and Metabolism, Ankara Guven Hospital, Turkey.
- 13 Department of Translational Medicine, University of Ferrara & Center for the Study and Treatment of Metabolic Diseases, Atherosclerosis, and Clinical Nutrition, University Hospital of Ferrara Arcispedale Sant'Anna, Italy.
- 14 Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Germany.
- 15 Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
- 16 Antwerp University Hospital, Belgium.
- 17 Medical University of Sofia, Saint Anna University Hospital, Departement of Cardiology, Bulgaria.
- 18 Canakkale Onsekiz Mart University, Medical Faculty Cardiology Dept, Turkey.
- 19 University of Health Sciences Dr. Siyami Ersek Hospital, Turkey.
- 20 Aalborg University, Denmark.
- 21 Nantes Université, CHU NANTES, CNRS, INSERM, l'institut du thorax, Nantes, France.
- 22 Universitätsklinikum Münster, Lipidambulanz, Germany.
- 23 Mersin University, Turkey.
- 24 Dept. of Cardiology, Haukeland, Unversity Hopsital, Norway.
- 25 Department for Internal Medicine I, Medical University Innsbruck, Austria.
- 26 Medical University of Vienna, Austria.
- 27 Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Germany.
- 28 Mater Dei Hospital, Malta.
- 29 Lipid Unit, Hospital de Sta Caterina, Spain.
- 30 Universitatea de Medicina si Farmacie Victor Babes din Timisoara & Clinica de Cardiologie, Institutul de Boli Cardiovasculare Timisoara, Romania.
- 31 Department of Pediatrics, Paracelsus Medical University, Austria.
- 32 Koç University School of Medicine Department of Cardiology, Turkey.
- 33 Hospital de Cascais - Dr.José de Almeida, Portugal.
- 34 University of Medicine and Pharmacy "Carol Davila", University and Emergency Hospital, Bucharest, Romania.
- 35 Grand Hôpital de Charleroi GHDC, Belgium.
- 36 Dept of Medical sciences, Uppsala University, Sweden.
- 37 Dept of Vascular Medicine, AmsterdamUMC, the Netherlands.
- 38 1th Department of Propedeutic Medicine, School of Medicine, National and Kapodistrian University of Athens, General Hospital of Athens Laiko, Greece.
- 39 CHU UCL Namur - Site Godinne, Belgium.
- 40 Azienda Ospedaliera di Rilievo Nazionale AORN Dei Colli, "V.Monaldi", Unit of Inherited and Rare Cardiovascular Diseases, Italy.
- 41 Center for the Study of Atherosclerosis, Bassini Hospital, Cinisello Balsamo, Italy.
- 42 Erciyes University, Turkey.
- 43 Department of Cardiology Odense University Hospital, Denmark.
- 44 1th Medical Department, Landstrasse Clinic, Vienna Health Association, Austria.
- 45 Clinica Medica Institute of "SS. Annunziata" Hospital, Department of Medicine and Aging Sciences, "G. d'Annunzio" University, Italy.
- 46 Hospital Lusíadas, Portugal.
- 47 Sorbonne Université, Groupe de Recherche Clinique Number 22, C2MV-Complications Cardiovasculaires et Métaboliques Chez les Patients Vivant avec le Virus de l'Immunodéficience Humaine, Institut National de la Santé et de la Recherche Médicale Unité Mixte de Recherche S 938, Centre de Recherche Saint-Antoine, Institut Hospital Universitaire de Cardio-métabolisme et Nutrition Cardiologie, Hôpital Saint Antoine Assistance Publique-Hôpitaux de Paris, Paris, France.
- 48 Cardiologie et Centre Clinico-Biologique des Lipides et Athérosclérose, CHU Rennes, France.
- 49 DBC St. Imre University Teaching Hospital, Metabolic Center, Lipid Center, Hungary.
- 50 Department of Clinical Medicine and Surgery, University of Naples Federico II, Italy.
- 51 Department of Clinical and Experimental Medicine - Lipid Center, University of Messina, Italy.
- 52 Dept Clinical Biochemistry, University Hospitals Bristol, United Kingdom.
- 53 Institute of Cardiology and Regenerative Medicine, University of Latvia & Latvian Center of Cardiology, Pauls Stradins Clinical University Hospital & Faculty of Medicine, University of Latvia, Latvia.
- 54 Division of Metabolic Disorders, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
- 55 Charles University Prague Medical Hospital in Pilsen, Czech Republic.
- 56 Central Manchester University Hospital NHS Foundation Trust, United Kingdom.
- 57 Department of Cardiology, Aarhus University Hospital, Denmark.
- 58 Department of Medicine, Division of Endocrinology and Diabetology, Medical University Graz, Austria.
- 59 Ankara Bilkent City Hospital, Turkey.
- 60 Department of Cardiology, Kafkas University Hospital, Faculty of Medicine, Turkey.
- 61 Center for Endocrinology, Diabetes and Preventive Medicine, University of Cologne, Faculty of Medicine and University Hospital Cologne, Germany.
- 62 Gaziantep University, Faculty of Medicine, Cardiology Department, Turkey.
- 63 CHUPORTO - Centro Hospitalar Universitário do Porto, Portugal.
- 64 Szent Gyorgy University Teaching Hospital of Fejer County, Hungary.
- 65 Children's University Hospital, Latvia.
- 66 Department of Internal Medicine, Erasmus MC University Medical Center, the Netherlands.
- 67 Institut de Recherche Expérimentale et Clinique, Universite Catholique de Louvain, Bruxelles, Belgium.
- 68 CHUC, Portugal.
- 69 Hospital Egas Moniz, Lisboa, Portugal.
- 70 AZ Maria Middelares Hospital Gent, Belgium.
- 71 Lipid and Arteriosclerosis Unit. Department of Internal Medicine, Hospital Universitario Reina Sofia, IMIBIC, University of Cordoba. CiberOBN, Spain.
- 72 Hospital La Paz-Carlos III, Spain.
- 73 Lithuanian University of Health sciences, Lithuania.
- 74 Eski?ehir Osmangazi University, Faculty of Medicine, Department of Cardiology, Turkey.
- 75 Department of Nutrition, University of Oslo and National Advisory Unit on FH, Oslo University Hospital, Norway.
- 76 The Lipid Clinic, Oslo University Hospital and Department of Nutrition, University of Oslo, Norway.
- 77 University Hospital of South Denmark, Esbjerg, Denmark.
- 78 Hacettepe University, Turkey.
- 79 1th Department of Medicine, Medical School, University of Pecs, Hungary.
- 80 Copenhagen University Hospital, Denmark.
- 81 IRCCS Multimedica, Italy.
- 82 Hospital Universitari Sant Joan, Universitat Rovira i Virgili, CIBERDEM, Reus, Spain.
- 83 University General Hospital Attikon, Greece.
- 84 Department of Preventive Cardiology and Lipidology, Medical University of Lodz, Poland.
- 85 Jagiellonian University Medical College, Dept. of Metabolic Diseases and Diabetology, Poland.
- 86 Franciscus Gasthuis & Vlietland, Rotterdam, the Netherlands.
- 87 Sapienza University of Rome, Italy.
- 88 North Estonia Medical Centre, Tallinn University of Technology, Estonia.
- 89 Unit for Cardiac and Cardiovascular Genetics, Oslo University Hospital, Norway.
- 90 Department of Endocrinology, Diabetes and Metabolism, University Children's Hospital, University Medical Centre Ljubljana, Slovenia.
- 91 Section of Internal Medicine, Angiology and Arteriosclerosis Diseases, Italy.
- 92 Department PROMISE-University of Palermo & Istituto di Biofisica, Consiglio Nazionale delle Ricerche, Palermo, Italy.
- 93 Ege University Medical School Department of Cardiology, Turkey.
- 94 Bispebjerg-Frederiksberg University Hospital, Denmark.
- 95 Department of Cardiology, Herlev and Gentofte Hospital, University of Copenhagen, Denmark.
- 96 3rd Department of Internal Medicine, General University Hospital and 1st Medical Faculty, Charles University, Prague, Czech Republic.
- 97 PEC2, University of Bourgogne Franche-Comté, France.
- 98 Dept. Laboratory Medicine, AZ St.Jan Hospital, Belgium.
- 99 Department of Clinical Biochemistry and Metabolic Medicine, Royal Liverpool University Hospital, United Kingdom.
- 100 Kartal Kosuyolu Research and Training Hospital, Turkey.
- 101 Lipid Clinic, Mater Dei Hospital & Dept of Medicine, University of Malta Medical School, Malta.
- 102 Internal Medicine, APSS Trento Hospital, Italy.
- 103 Dept. of Internal Medicine, Radboud University Medical Center, the Netherlands.
- 104 UMHAT Alexandrovska, Bulgaria.
- 105 Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Lithuania.
- 106 NSC "Institute of Cardiology, Clinical and Regenerative Medicine of the NAMS of Ukraine", Ukraine.
- 107 Universitätsklinikum Jena, Department of Internal Medicine I, Germany.
- 108 University of Health Sciences, Izmir Faculty of Medicine, Tepecik Training and Research Hospital, Department of Cardiology, Turkey.
- 109 Hospital Virgen del Rocío, Spain.
- 110 Mugla Sitki Kocman University, Faculty of Medicine, Cardiology Department, Turkey.
- 111 University Hospitals of Leicester, United Kingdom.
- 112 Cardio Metabolic Unit, Karolinska Institutet, And Theme Inflammation and Ageing, Karolinska University Hospital Huddinge, Sweden.
- 113 Department of Internal Medicine and Rare disease Centre "C. Frugoni" University Hospital of Bari, Bari, Italy.
- 114 Salisbury NHS Foundation trust, United Kingdom.
- 115 Metabolic Center General University Hospital, Czech Republic.
- 116 Dept.of Internal Medicine, Third Faculty of Medicine, Charles University and Královské Vinohrady University Hospital Prague, Czech Republic.
- 117 Department of Cardiology, Cardiovascular Unit, J. Stru? Hospital, Poznań & Department of Hypertension, Angiology and Internal Medicine, Poznan University of Medical Sciences, Poznań, Poland.
- 118 Hospital VIRGEN DE LA VICTORIA, Spain.
- 119 Instituto Cuf, Portugal.
- 120 5th Med. Dept, Clinic Ottakring, Austria.
- 121 Hospices Civils de Lyon, INSERM, Université Lyon1, Hôpital Louis Pradel, Fédération d'endocrinologie, France.
- 122 Medical University Vienna, Austria.
- 123 Center for Cardiovascular Prevention, Charles University in Prague, First Faculty of Medicine and Thomayer University Hospital, Prague, Czech Republic.
- 124 Aix Marseille Univ, APHM, INSERM, INRAE, C2VN, University Hospital La Conception, Department of Nutrition, Metabolic Diseases and Endocrinology, France.
- 125 Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
- 126 Internal Medicine, Obezita-Ormiga s.r.o, Czech Republic.
- 127 Klaip?da Seamen's Hospital, Lithuania.
- 128 Department of Paramedic science, Medical diagnostics studies and Public Health, Faculty of Health Care Studies, University of West Bohemia, Czech Republic.
- 129 Department of Medicine - DIMED, University of Padova, Italy.
- 130 University of Bologna, IRCCS S.Orsola Bologna, Italy.
- 131 Lipidova ambulance, Czech Republic.
- 132 Gothenburg University, Sweden.
- 133 Department of Internal Medicine B, University Medicine Greifswald, DZHK, Germany.
- 134 Clinical Division of Pediatric Pulmonology, Allergology and Endocrinology, Department of Pediatrics and Adolescent Medicine, Medical University, Vienna, Austria.
- 135 Clinical Division of Endocrinology and Metabolism, Department of Medicine III, Medical University Vienna & Third Medical Department and Karl Landsteiner Institute for Metabolic Diseases and Nephrology, Clinic Hietzing, Vienna, Austria.
- 136 Dept of Cardiology, Linköping University Hospital, Sweden.
- 137 Consultant Cardiologist, Royal Brompton and Harefield Hospitals Part of Guy's and St Thomas' NHS Foundation Trust, United Kingdom.
- 138 Centre of Cardiovascular Surgery and Transplantation, Brno & Medical Faculty, Masaryk University, Brno, Czech Republic.
- 139 Metabolic Clinic, Tomas Bata Hospital, Zlín, Czech Republic.
- 140 Republican Panevezys Hospital, Dep. of Cardiology, Lithuania.
- 141 Klinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Germany.
- 142 University Hospital Carl Gustav Carus Dresden at the Technical University Dresden, Department of Internal Medicine III, Germany.
- 143 UMC - University Children's Hospital Ljubljana, University of Ljubljana, Faculty of Medicine, Slovenia.
- 144 Hospital Universitario Miguel Servet, IISA, CIBERCV, Spain.
- 145 Advanced Lipid Management and Research ALMAR Centre, Tallaght University Hospital, Ireland.
- 146 University Hospital Hradec Králové and Charles University, Faculty of Medicine in Hradec Králové, 3rd Department of Internal Medicine - Metabolism and Gerontology, Czech Republic.
- 147 Department of Clinical Biochemistry, St. Anne's University Hospital Brno, 2nd Clinic of Internal Medicine, Faculty of Medicine, Masaryk University Brno, Czech Republic.
- 148 Centre of Nephrology Göttingen, Germany.
- 149 SUS Malmoe, Sweden.
- 150 Hospital Universitari de Bellvitge-Idibell-UB-CiberObn, Spain.
- 151 Second Cardiology Clinic, University Hospital Sv. Marina, Medical University of Varna, Bulgaria.
- 152 Vilnius University Medical Faculty, Vilnius University Hospital Santaros klinikos, Lithuania.
- 153 Department for Metabolic Diseases, University Hospital Center Zagreb, Croatia.
- PMID: 36894469
- DOI: 10.1016/j.atherosclerosis.2023.02.007
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Abstract
Background and aims: The European Atherosclerosis Society (EAS) Lipid Clinics Network promoted a survey in order to identify and understand how and when lipoprotein(a) [Lp(a)] is tested and clinically evaluated in lipid clinics throughout Europe, and the challenges that may prevent evaluation from being carried out.
Methods: This survey was divided into three areas of inquiry: background and clinical setting information of clinicians, questions for doctors who claimed not to measure Lp(a), in order to understand what were the reasons for not ordering the test, and questions for doctors who measure Lp(a), to investigate the use of this value in the management of patients.
Results: A total of 151 centres clinicians filled in the survey, out of 226 invited. The proportion of clinicians who declare to routinely measure Lp(a) in clinical practice was 75.5%. The most common reasons for not ordering the Lp(a) test were the lack of reimbursement or of treatment options, the non-availability of Lp(a) test, and the high cost of performing the laboratory test. The availability of therapies targeting this lipoprotein would result in a greater propensity of clinicians to start testing Lp(a). Among those who declared to routinely measure Lp(a), the Lp(a) measurement is mostly requested to further stratify patients' cardiovascular risk, and half of them recognized 50 mg/dL (approx. 110 nmol/L) as the threshold for increased cardiovascular risk due.
Conclusions: These results warrant for a great deal of effort from scientific societies to address the barriers that limit the routine use of the measurement of Lp(a) concentration and to recognise the importance of Lp(a) as a risk factor.
Keywords: Cardiovascular risk; Clinical evaluation; Clinicians; Lipoprotein(a).
Copyright © 2023 Elsevier B.V. All rights reserved.
Conflict of interest statement
Declaration of competing interest All authors declare no support from any organization for the submitted work; no other relationships or activities that could appear to have influenced the submitted work. E.O., M.G., and M.C. report no disclosures. A.L.C. received research funding and/or honoraria for advisory boards, consultancy or speaker bureau from Aegerion, Amgen, AstraZeneca, Eli Lilly, Genzyme, Mediolanum, Merck or MSD, Pfizer, Recordati, Rottapharm, Sanofi-Regeneron, Sigma-Tau. L.T. received research funding and/or honoraria for advisory boards, consultancy or speaker bureau from Abbott, Astra Zeneca, Novartis, Sanofi, MSD, Novo Nordisk, Amgen, Bayer, Daiichi Sankyo, Janssen, Pfizer, Recordati. M.B. speakers bureau: Amgen, Daichii-Sankyo, KRKA, Polpharma, Mylan/Viatris, Novartis, Novo-Nordisk, Pfizer, Sanofi-Aventis, Teva, Zentiva; consultant to Amgen, Daichii Sankyo, Esperion, Freia Pharmaceuticals, NewAmsterdam, Novartis, Novo-Nordisk, Polfarmex, Sanofi-Aventis; Grants from Amgen, Daichii-Sankyo, Mylan/Viatris, Sanofi and Valeant; CMDO at Longevity Group (Luxemburg). K.K.R. received research funding and/or honoraria for advisory boards, consultancy or speaker bureau from Amgen, Daiichi Sankyo, Regeneron, Sanofi, Novartis, Esperion, Abbott, Bayer, Eli Lilly, Silence Therapeutics, CSL Behring, New Amsterdam Pharma, Novo Nordisk, BI, Scribe, Vaxxinity, CRISPR, AZ, Kowa, Cargene and Viatris.
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