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. 2023 Mar 3:17:531-545.
doi: 10.2147/PPA.S395327. eCollection 2023.

Factors Affecting Patient Adherence to Inhalation Therapy: An Application of SEIPS Model 2.0

Jing Ma  1 , Xu Sun  1   2 , Xinwei Wang  1   2 , Bingjian Liu  1   2 , Kaiqi Shi  3
Affiliations

Factors Affecting Patient Adherence to Inhalation Therapy: An Application of SEIPS Model 2.0

Jing Ma et al. Patient Prefer Adherence. .

Abstract

Purpose: This study aims to explore factors that affect patient adherence to inhalation therapy by applying a patient-centered approach.

Patients and methods: We conducted a qualitative study to identify the factors that influence adherent behaviors among asthma/COPD patients. 35 semi-structured interviews with patients, and 15 semi-structured interviews with healthcare providers (HCPs) who manage asthma/COPD patients were conducted. The SEIPS 2.0 model was applied as a conceptual framework for guiding the interview content and analysis of the interview data.

Results: Based on the findings of this study, a conceptual framework of patient adherence in asthma/COPD during inhalation therapy was constructed including five themes: person, task, tool, physical environment, and culture and society. Person-related factors include patient ability and emotional experience. Task-related factors refer to task type and frequency and flexibility. Tool-related factors are the type of inhalers and usability of inhalers. Physical environment-related factors include home environment and COVID-19 situation. Culture and social related factors consist of two aspects: cultural beliefs and social stigma.

Conclusion: The findings of the study identified 10 influential factors that impact on patient adherence to inhalation therapy. A SEIPS-based conceptual model was constructed based on the responses of patients and HCPs to explore the experiences of patients engaging in inhalation therapy and interacting with inhalation devices. In particular, new insight about factors of emotional experience, physical environment and traditional cultural beliefs were found crucial for patients with Asthma/COPD to conduct patients' adherent behaviors.

Keywords: adherence; asthma; chronic obstructive pulmonary disease; drug-device combination products; human factors and ergonomics; inhalation therapy.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Flow chart of participants.
Figure 2
Figure 2
Patient adherence to inhalation therapy work system model.
See this image and copyright information in PMC

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