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Case Reports
. 2023 Feb;14(2):59-63.
doi: 10.14740/jmc4044. Epub 2023 Feb 25.

Chronic Oral Amiodarone as a Cause of Acute Liver Failure

Evelyn Calderon-Martinez  1 , Samanta Landazuri-Navas  2 , Gizem Kaya  1 , John Cinicola  1
Affiliations
Case Reports

Chronic Oral Amiodarone as a Cause of Acute Liver Failure

Evelyn Calderon-Martinez et al. J Med Cases. 2023 Feb.

Abstract

Acute liver failure (ALF) is a rare condition that can have a variable clinical course and potentially fatal outcomes. Medication toxicity is a known etiology, however liver failure induced by amiodarone is rare and has been reported mostly in the setting of intravenous (IV) infusion. We present an 84-year-old patient who developed ALF after chronic use of oral amiodarone. The patient received supportive care and her symptoms improved.

Keywords: Acute liver failure; Adverse reaction; Amiodarone; Hepatotoxicity.

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Conflict of interest statement

The authors do not have any conflict of interest.

Figures

Figure 1
Figure 1
Liver function test (LFT) trending before and after admission. AST: aspartate aminotransferase; ALT: alanine aminotransferase.
See this image and copyright information in PMC

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