Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2023 Jun;307(6):1873-1882.
doi: 10.1007/s00404-023-06993-y. Epub 2023 Mar 10.

A comparison of special intrauterine balloons and intrauterine contraceptive devices in the treatment of intrauterine adhesions

Affiliations
Comparative Study

A comparison of special intrauterine balloons and intrauterine contraceptive devices in the treatment of intrauterine adhesions

Lin-Lin Zhuang et al. Arch Gynecol Obstet. 2023 Jun.

Abstract

Purpose: This study aimed to compare the efficacy of a special kind of intrauterine balloon (IUB) and that of an intrauterine contraception device (IUD) for patients with intrauterine adhesions (IUAs) after transcervical resection of adhesion (TCRA).

Methods: In this retrospective cohort study, after TCRA, 31 patients received a special IUB, and 38 patients received an IUD. The Fisher exact test, logistic regression method, Kaplan-Meier method and Cox proportional hazards regression model were used for statistical analysis. A two-sided value of P < 0.05 was considered statistically significant.

Results: The readhesion rate significantly differed between the IUB group and IUD group, at 15.39% and 54.06%, respectively (P = 0.002). For recurrent moderate IUA, patients in the IUB group had lower scores than patients in the IUD group (P = 0.035). There was a significant difference in the intrauterine pregnancy rate of IUA patients in the IUB group and IUD group after treatment, with rates of 55.56% and 14.29%, respectively (P = 0.015).

Conclusion: Patients in the special IUB group had better outcomes than those in the IUD group, which has a certain guiding significance for clinical work.

Keywords: Hysteroscopy; Intrauterine adhesions; Intrauterine contraception device; Special intrauterine balloon.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest. All authors confirm that all methods were carried out in accordance with the relevant guidelines and regulations.

Figures

Fig. 1
Fig. 1
Special intrauterine ballon (A), heart-shaped copper IUD (B)
Fig. 2
Fig. 2
Cumulative conception rate after TCRA in IUA patients treated with IUB or IUD

References

    1. Sanad AS, Aboulfotouh ME. Hysteroscopic adhesiolysis: efficacy and safety. Arch Gynecol Obstet. 2016;294:411–416. doi: 10.1007/s00404-016-4107-9. - DOI - PubMed
    1. Lin XN, Wei ML, Li TC, Huang QX, Huang D, Zhou F, Zhang SY. A comparison of intrauterine balloon, intrauterine contraceptive device and hyaluronic acid gel in the prevention of adhesion reformation following hysteroscopic surgery for Asherman syndrome: a cohort study. Eur J Obstet Gynecol Reprod Biol. 2013;170(2):512–516. doi: 10.1016/j.ejogrb.2013.07.018. - DOI - PubMed
    1. Deans R, Abbott J. Review of intrauterine adhesions. J Minim Invas Gynecol. 2010;17(5):555–569. doi: 10.1016/j.jmig.2010.04.016. - DOI - PubMed
    1. Yu D, Wong YM, Cheong Y, Xia EL, Li TC. Asherman syndrome-one century later. Fertil Steril. 2008;89(4):759–779. doi: 10.1016/j.fertnstert.2008.02.096. - DOI - PubMed
    1. Zhang XM, Liu W, Zhou Y, Qiu JX, Sun YJ, Li M, Ding YQ, Xi QH. Comparison of therapeutic efficacy of three methods to prevent re-adhesion after hysteroscopic intrauterine adhesion separation: a parallel, randomized and single-center trial. Ann Palliat Med. 2021;10(6):6804–6823. doi: 10.21037/apm-21-1296. - DOI - PubMed

Publication types