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Meta-Analysis
. 2023 Mar 10;102(10):e33153.
doi: 10.1097/MD.0000000000033153.

Risk factors for post-extubation dysphagia in ICU: A systematic review and meta-analysis

Lingyu Hou  1 , Ying Li  2 , Jianhua Wang  2 , Yuqi Wang  2 , Jingchao Wang  2 , GuoJing Hu  2 , Xiao Rong Ding  1
Affiliations
Meta-Analysis

Risk factors for post-extubation dysphagia in ICU: A systematic review and meta-analysis

Lingyu Hou et al. Medicine (Baltimore). .

Abstract

Background: Post-extubation dysphagia is high in critically ill patients and is not easily recognized. This study aimed to identify risk factors for acquired swallowing disorders in the intensive care unit (ICU).

Methods: We have retrieved all relevant research published before August 2022 from PubMed, Embase, Web of Science, and the Cochrane Library electronic databases. The studies were selected using inclusion and exclusion criteria. Two reviewers screened studies, extracted data, and independently evaluated the risk of bias. The quality of the study was assessed with the Newcastle-Ottawa Scale, and a meta-analysis was carried out with Cochrane Collaboration's Revman 5.3 software.

Results: A total of 15 studies were included. Age (odds ratio [OR] = 1.04), tracheal intubation time (OR = 1.61), APACHE II (OR = 1.04), and tracheostomy (OR = 3.75) were significant risk factors that contributed to post-extubation dysphagia in ICU.

Conclusion: This study provides preliminary evidence that post-extraction dysphagia in ICU is associated with factors such as age, tracheal intubation time, APACHE II, and tracheostomy. The results of this research may improve clinician awareness, risk stratification, and prevention of post-extraction dysphagia in the ICU.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1.
Figure 1.
Forest plot analysis of age.
Figure 2.
Figure 2.
Forest plot analysis of tracheal intubation time.
Figure 3.
Figure 3.
Forest plot analysis of APACHE II.
Figure 4.
Figure 4.
Forest plot analysis of tracheostomy.
See this image and copyright information in PMC

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