. 2023 Mar 10;27(1):101.

doi: 10.1186/s13054-023-04398-6.

The clinical frailty scale, but not the FRAIL checklist is associated with mortality in old critically ill patients with COVID-19

Bernhard Wernly^{1

2}, Hans Flaatten³, Susannah Leaver⁴, Bertrand Guidet⁵, Christian Jung⁶; COVIP investigators

Collaborators, Affiliations

Collaborators

COVIP investigators:
Jesper Fjølner, Michael Beil, Sandra Oeyen, Wojtek Szczeklik, Muhammed Elhadi, Sigal Sviri, Dylan deLange, Rui Moreno, Antonio Artigas, David Dudzinski, Nicolas Serck, Helene Korvenius Nedergaard, Iman Shaat, Aliae Mohamed Hussein, Mostafa Zanaty, Ebtisam Hassanin, Aliae Mohamed Hussein, Nouralsabah Mohamed, Marwa Omar, Ghada Atef Ali Abd El-Wahed, Shimaa Touny, Avinash Aujayeb, Saad Nseir, Thomas Urbina, Pierre Garcon, Jean-Philippe Rigaud, Thierry Vanderlinden, Xavier Valette, Buno Megarbane, Elodie Baron, Olivier Nigeon, Gaetan Plantefeve, Camille Foucault, Mehran Monchi, Kristina Fuest, Raphael Bruno, Malte Kelm, Hans-Joachim Kabitz, Stefan Schaller, Abdurraouf Abusalama, Hussein Embarek, Mohamed Anaiba, Ahmed Taher, Akram Alkaseek, Mirjam Evers, Willem Dieperink, Alexander Daniel Cornet, Filipa Brochado, Sonia Lopez-Cuenca, Mohammad Aldiabat, Mohammed Al-Sadawi

Affiliations

¹ Department of Internal Medicine, General Hospital Oberndorf, Teaching Hospital of the Paracelsus Medical University Salzburg, Salzburg, Austria.
² Center for Public Health and Healthcare Research, Paracelsus Medical University of Salzburg, Salzburg, Austria.
³ Department of Research and Development, Haukeland University Hospital, University of Bergen, Bergen, Norway.
⁴ General Intensive Care, St. George's University Hospital NHS Foundation Trust, London, UK.
⁵ Service de Réanimation Médicale, Hôpital Saint-Antoine, Institut Pierre-Louis d'épidémiologie et de santé publique, Hôpital Saint-Antoine, Sorbonne Université, Paris, France.
⁶ Division of Cardiology, Pulmonology, and Vascular Medicine, Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine University Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany. christian.jung@med.uni-duesseldorf.de.

PMID: 36899440
PMCID: PMC10004437
DOI: 10.1186/s13054-023-04398-6

The clinical frailty scale, but not the FRAIL checklist is associated with mortality in old critically ill patients with COVID-19

Bernhard Wernly et al. Crit Care. 2023.

. 2023 Mar 10;27(1):101.

doi: 10.1186/s13054-023-04398-6.

Authors

Bernhard Wernly^{1

2}, Hans Flaatten³, Susannah Leaver⁴, Bertrand Guidet⁵, Christian Jung⁶; COVIP investigators

Collaborators

COVIP investigators:
Jesper Fjølner, Michael Beil, Sandra Oeyen, Wojtek Szczeklik, Muhammed Elhadi, Sigal Sviri, Dylan deLange, Rui Moreno, Antonio Artigas, David Dudzinski, Nicolas Serck, Helene Korvenius Nedergaard, Iman Shaat, Aliae Mohamed Hussein, Mostafa Zanaty, Ebtisam Hassanin, Aliae Mohamed Hussein, Nouralsabah Mohamed, Marwa Omar, Ghada Atef Ali Abd El-Wahed, Shimaa Touny, Avinash Aujayeb, Saad Nseir, Thomas Urbina, Pierre Garcon, Jean-Philippe Rigaud, Thierry Vanderlinden, Xavier Valette, Buno Megarbane, Elodie Baron, Olivier Nigeon, Gaetan Plantefeve, Camille Foucault, Mehran Monchi, Kristina Fuest, Raphael Bruno, Malte Kelm, Hans-Joachim Kabitz, Stefan Schaller, Abdurraouf Abusalama, Hussein Embarek, Mohamed Anaiba, Ahmed Taher, Akram Alkaseek, Mirjam Evers, Willem Dieperink, Alexander Daniel Cornet, Filipa Brochado, Sonia Lopez-Cuenca, Mohammad Aldiabat, Mohammed Al-Sadawi

Affiliations

¹ Department of Internal Medicine, General Hospital Oberndorf, Teaching Hospital of the Paracelsus Medical University Salzburg, Salzburg, Austria.
² Center for Public Health and Healthcare Research, Paracelsus Medical University of Salzburg, Salzburg, Austria.
³ Department of Research and Development, Haukeland University Hospital, University of Bergen, Bergen, Norway.
⁴ General Intensive Care, St. George's University Hospital NHS Foundation Trust, London, UK.
⁵ Service de Réanimation Médicale, Hôpital Saint-Antoine, Institut Pierre-Louis d'épidémiologie et de santé publique, Hôpital Saint-Antoine, Sorbonne Université, Paris, France.
⁶ Division of Cardiology, Pulmonology, and Vascular Medicine, Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine University Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany. christian.jung@med.uni-duesseldorf.de.

PMID: 36899440
PMCID: PMC10004437
DOI: 10.1186/s13054-023-04398-6

No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

**Fig. 1**
Frail patients defined by both CFS > 4 (HR 2.01 95% CI 1.50–2.69; p < 0.001; A and FRAIL > 0 (HR 1.46; 95% CI 1.04–2.03; p = 0.03; B evidenced worse outcomes

See this image and copyright information in PMC

Cited by

Clinical Frailty Scale and the FRAIL checklist: Can they complement each other?
Cheung EH, Cheung JC, Yip YY. Cheung EH, et al. Crit Care. 2023 May 4;27(1):171. doi: 10.1186/s13054-023-04451-4. Crit Care. 2023. PMID: 37143077 Free PMC article. No abstract available.
Improving frailty assessment: the task is not finished.
Wernly B, Flaatten H, Leaver S, Guidet B, Jung C; COVIP investigators. Wernly B, et al. Crit Care. 2023 Jun 1;27(1):218. doi: 10.1186/s13054-023-04477-8. Crit Care. 2023. PMID: 37264423 Free PMC article. No abstract available.
The truism of 'life limiting illness' in ICU.
Subramaniam A, Ling RR, Darvall J. Subramaniam A, et al. Crit Care Resusc. 2024 Jun 28;26(2):61-63. doi: 10.1016/j.ccrj.2024.06.003. eCollection 2024 Jun. Crit Care Resusc. 2024. PMID: 39072239 Free PMC article. No abstract available.

References

1. Jung C, Guidet B, Flaatten H, VIP study group Frailty in intensive care medicine must be measured, interpreted and taken into account! Intensiv Care Med. 2022;49:1–4. - PMC - PubMed
1. Jung C, Flaatten H, Fjølner J, et al. The impact of frailty on survival in elderly intensive care patients with COVID-19: the COVIP study. Crit Care. 2021;25:149. doi: 10.1186/s13054-021-03551-3. - DOI - PMC - PubMed
1. Guidet B, Flaatten H, Boumendil A, et al. Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit. Intensiv Care Med. 2018;44:1027–1038. doi: 10.1007/s00134-018-5196-7. - DOI - PubMed
1. Flaatten H, Guidet B, Andersen FH, et al. Reliability of the clinical frailty scale in very elderly ICU patients: a prospective European study. Ann Intensiv Care. 2021;11:22. doi: 10.1186/s13613-021-00815-7. - DOI - PMC - PubMed
1. Cheung EH-L, Cheung JC-H, Yip Y-Y. Raising awareness for time-limited trial discussion upon ICU triage and admission. Intensiv Care Med. 2022;48:240–241. doi: 10.1007/s00134-021-06590-0. - DOI - PMC - PubMed

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The clinical frailty scale, but not the FRAIL checklist is associated with mortality in old critically ill patients with COVID-19

Collaborators

Affiliations

The clinical frailty scale, but not the FRAIL checklist is associated with mortality in old critically ill patients with COVID-19

Authors

Collaborators

Affiliations

Conflict of interest statement

Figures

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References

Publication types

MeSH terms

LinkOut - more resources

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Medical