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. 2023 Feb 24:4:100163.
doi: 10.1016/j.cccb.2023.100163. eCollection 2023.

Language discordance as a marker of disparities in cerebrovascular risk and stroke outcomes: A multi-center Canadian study

Ryan T Muir  1 , Arunima Kapoor  1 , Megan L Cayley  1 , Michelle N Sicard  1 , Karen Lien  1 , Alisia Southwell  1 , Dar Dowlatshahi  2 , Demetrios J Sahlas  3 , Gustavo Saposnik  4 , Jennifer Mandzia  5 , Leanne K Casaubon  6 , Ayman Hassan  7 , Yael Perez  8 , Daniel Selchen  4 , Brian J Murray  1   9 , Krista Lanctot  9   10 , Moira K Kapral  9   11   12   13 , Nathan Herrmann  9   10 , Stephen Strother  14 , Amy Y X Yu  1   9   12   13 , Peter C Austin  12   13 , Susan E Bronskill  9   12   13 , Richard H Swartz  1   9   12
Affiliations

Language discordance as a marker of disparities in cerebrovascular risk and stroke outcomes: A multi-center Canadian study

Ryan T Muir et al. Cereb Circ Cogn Behav. .

Abstract

Background: Differences in ischemic stroke outcomes occur in those with limited English proficiency. These health disparities might arise when a patient's spoken language is discordant from the primary language utilized by the health system. Language concordance is an understudied concept. We examined whether language concordance is associated with differences in vascular risk or post-stroke functional outcomes, depression, obstructive sleep apnea and cognitive impairment.

Methods: This was a multi-center observational cross-sectional cohort study. Patients with ischemic stroke/transient ischemic attack (TIA) were consecutively recruited across eight regional stroke centers in Ontario, Canada (2012 - 2018). Participants were language concordant (LC) if they spoke English as their native language, ESL if they used English as a second language, or language discordant (LD) if non-English speaking and requiring translation.

Results: 8156 screened patients. 6,556 met inclusion criteria: 5067 LC, 1207 ESL and 282 LD. Compared to LC patients: (i) ESL had increased odds of diabetes (OR = 1.28, p = 0.002), dyslipidemia (OR = 1.20, p = 0.007), and hypertension (OR = 1.37, p<0.001) (ii) LD speaking patients had an increased odds of having dyslipidemia (OR = 1.35, p = 0.034), hypertension (OR = 1.37, p<0.001), and worse functional outcome (OR = 1.66, p<0.0001). ESL (OR = 1.88, p<0.0001) and LD (OR = 1.71, p<0.0001) patients were more likely to have lower cognitive scores. No associations were noted with obstructive sleep apnea (OSA) or depression.

Conclusions: Measuring language concordance in stroke/TIA reveals differences in neurovascular risk and functional outcome among patients with limited proficiency in the primary language of their health system. Lower cognitive scores must be interpreted with caution as they may be influenced by translation and/or greater vascular risk. Language concordance is a simple, readily available marker to identify those at risk of worse functional outcome. Stroke systems and practitioners must now study why these differences exist and devise adaptive care models, treatments and education strategies to mitigate barriers influenced by language discordance.

Keywords: Cognitive impairment; Depression; Language concordance; Obstructive sleep apnea; Stroke; Transient ischemic attack; Vascular risk factors.

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
Patient Inclusion Flowchart.
See this image and copyright information in PMC

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