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Editorial
. 2023 Feb 13;15(1):71-73.
doi: 10.1007/s12551-023-01045-w. eCollection 2023 Feb.

Gobind: an inspiring enigma

Gopala Krishna Aradhyam  1 , Naranamangalam R Jagannathan  2   3   4
Affiliations
Editorial

Gobind: an inspiring enigma

Gopala Krishna Aradhyam et al. Biophys Rev. .

Abstract

Gobind Khorana's distinguished career spanned nearly six decades (1952-2011). His work resulted in remarkable achievements starting with the complicated synthesis of coenzyme A. He then pioneered the synthesis of DNA oligonucleotides, which enabled him to crack the genetic code. Using this experience, he ventured to accomplish the first complete synthesis of a gene. Not satisfied with elucidating the function of bacteriorhodopsin, Gobind took up another greater challenge, that of spearheading studies on visual rhodopsin, its mechanism of activation, and the consequent signal transduction pathway. This Editorial acts to introduce the articles appearing in this Issue Focus dedicated to celebrating the 100th anniversary of the year of his birth.

Keywords: Har Gobind Khorana.

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Conflict of interest statement

Conflict of interestThe authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Drawing of Har Gobind Khorana: courtesy of Mr. Paras Gautam who is a first year PhD scholar in the structural biology lab, Department of Biotechnology, IIT Madras
See this image and copyright information in PMC

References

    1. Klein-Seetharaman J (2023) Gobind’s last graduate student. Biophys Rev 15 (Current Issue). 10.1007/s12551-023-01047-8 - PMC - PubMed
    1. Krishna AG, Naranamangalam JR (2023) Gobind: an inspiring enigma. Biophys Rev 15 (Current Issue). 10.1007/s12551-023-01045-w - PMC - PubMed
    1. Murali S, Krishna AG (2023) Structure-function relationship and physiological role of apelin and its G protein coupled receptor. Biophy Rev 15 (Current Issue). 10.1007/s12551-023-01044-x - PMC - PubMed
    1. Reeves PJ (2023) Expression systems for bovine rhodopsin: a review of the progress made in the Khorana laboratory. Biophys Rev (Current Issue). 10.1007/s12551-022-01037-2 - PMC - PubMed
    1. Rothschild KJ (2023) My remembrances of H.G. Khorana: exploring the mechanism of bacteriorhodopsin with site-directed mutagenesis and FTIR difference spectroscopy. Biophys Rev (Current Issue). 10.1007/s12551-023-01046-9 - PMC - PubMed

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