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. 1987;45(3-4):187-90.
doi: 10.1159/000132452.

Rearrangements of chromosome region 12q13----q15 in pleomorphic adenomas of the human salivary gland (PSA)

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Rearrangements of chromosome region 12q13----q15 in pleomorphic adenomas of the human salivary gland (PSA)

J Bullerdiek et al. Cytogenet Cell Genet. 1987.

Abstract

Nine of 40 pleomorphic salivary gland adenomas (PSAs) showed clonal aberrations of chromosome 12, with a breakpoint at 12q13----q15. The cytogenetic findings in these cases and those of nine additional cases reported in the literature suggest that this type of aberration is a primary change directly involved in the genesis of PSA.

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