Rearrangements of chromosome region 12q13----q15 in pleomorphic adenomas of the human salivary gland (PSA)
- PMID: 3691185
- DOI: 10.1159/000132452
Rearrangements of chromosome region 12q13----q15 in pleomorphic adenomas of the human salivary gland (PSA)
Abstract
Nine of 40 pleomorphic salivary gland adenomas (PSAs) showed clonal aberrations of chromosome 12, with a breakpoint at 12q13----q15. The cytogenetic findings in these cases and those of nine additional cases reported in the literature suggest that this type of aberration is a primary change directly involved in the genesis of PSA.
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