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Case Reports
. 2023 Mar 9;11(1):e5-e9.
doi: 10.1055/s-0043-1764289. eCollection 2023 Jan.

Endobronchial Inflammatory Myofibroblastic Tumor in a 3-Year-Old Child

Riccardo Guanà  1 , Andrea Carpino  1 , Marta Miglietta  1 , Elisa Zambaiti  1 , Alessia Cerrina  1 , Luca Lonati  1 , Francesco Guerrera  1 , Stefano Vallero  1 , Salvatore Garofalo  1 , Marco Bardessono  1 , Francesca Maletta  1 , Steffi Shilly  2 , Fabrizio Gennari  1
Affiliations
Case Reports

Endobronchial Inflammatory Myofibroblastic Tumor in a 3-Year-Old Child

Riccardo Guanà et al. European J Pediatr Surg Rep. .

Abstract

Inflammatory myofibroblastic tumor (IMT) is a mesenchymal tumor that can occur at any age. However, it is primarily seen in children, with the most common site being in the lung parenchyma, usually present with rare endobronchial lesions. This case reports the incidence in a 3-year-old girl diagnosed with pericardiac pneumonia treated with antibiotics with no clinical improvement. A chest computed tomography (CT) scan identified a 1.5-cm lesion in the left main bronchus. Bronchoscopy revealed complete obstruction of the left main stem bronchus. A left posterolateral thoracotomy was performed. Additionally, a left sleeve upper bronchial resection was conducted under fibroendoscopic control. Definitive histology confirmed IMT. After 2 years of endoscopic follow-up, there is no evidence of recurrence.

Keywords: bronchoscopy; myofibroblastic tumor; thoracotomy.

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Conflict of interest statement

Conflict of Interest All authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
CT scan images of IMT.
Fig. 2
Fig. 2
Endoscopic appearance of the endoluminal lesion in the left main bronchus, obliterating almost all the bronchial lumen.
Fig. 3
Fig. 3
Schematic drawing of the surgical resection.
Fig. 4
Fig. 4
The endobronchial lesion is seen at low magnification (20 × ) as a polypoid mass protruding in the bronchial lumen ( A ); the lesion has a moderate cellularity with a fibrohistiocytic appearance composed by spindle cells (myofibroblasts) and a variable numbers of plasma cells, lymphocytes, histiocytes admixed; the stroma is focally myxoid (magnification 200 × ) ( B, C ).
See this image and copyright information in PMC

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