Counseling on hormone replacement therapy: the real risks and benefits
- PMID: 36912256
- DOI: 10.1097/GCO.0000000000000843
Counseling on hormone replacement therapy: the real risks and benefits
Abstract
Purpose of review: The menopause transition can be a time of great upheaval and suffering for some patients. Hormone replacement therapy (HRT) can relieve symptoms and improve quality of life but the perceived risks of HRT have decreased use over the past two decades. Understanding the real risks and benefits will ease physician and other healthcare professionals discomfort with counseling and prescribing this potentially life changing therapy in appropriate patients.
Recent findings: Menopausal symptoms may persist several years beyond the final menstrual period. Previously stated risks of HRT overestimated the concern with menopausal therapy. New data indicates there are medical benefits to HRT beyond quality of life measures.
Summary: In appropriate patients, the benefits of hormone replacement therapy outweigh the risks. Extended use of hormone replacement therapy is reasonable in patients with persistent symptoms.
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
Similar articles
-
Counseling in menopausal women: How to address the benefits and risks of menopause hormone therapy. A FIGO position paper.Int J Gynaecol Obstet. 2024 Feb;164(2):516-530. doi: 10.1002/ijgo.15278. Epub 2024 Jan 4. Int J Gynaecol Obstet. 2024. PMID: 38178609
-
Hormone therapy in the postmenopausal years: considering benefits and risks in clinical practice.Hum Reprod Update. 2021 Oct 18;27(6):1115-1150. doi: 10.1093/humupd/dmab026. Hum Reprod Update. 2021. PMID: 34432008 Clinical Trial.
-
Hormone replacement therapy - Current recommendations.Best Pract Res Clin Obstet Gynaecol. 2022 May;81:8-21. doi: 10.1016/j.bpobgyn.2021.12.001. Epub 2021 Dec 14. Best Pract Res Clin Obstet Gynaecol. 2022. PMID: 35000809 Review.
-
Influence of Menopausal Hormone Therapy on the Breast: Counseling Your Patients Before You Prescribe.J Womens Health (Larchmt). 2022 Feb;31(2):167-170. doi: 10.1089/jwh.2021.0322. Epub 2021 Nov 17. J Womens Health (Larchmt). 2022. PMID: 34788572
-
Hormone replacement therapy and menopause: a review of randomized, double-blind, placebo-controlled trials.Kaohsiung J Med Sci. 2003 Jun;19(6):257-70. doi: 10.1016/S1607-551X(09)70472-3. Kaohsiung J Med Sci. 2003. PMID: 12873034 Free PMC article. Review.
Cited by
-
Estrogen: the forgotten player in metaflammation.Front Pharmacol. 2024 Nov 7;15:1478819. doi: 10.3389/fphar.2024.1478819. eCollection 2024. Front Pharmacol. 2024. PMID: 39575382 Free PMC article. Review.
References
-
- Stefanick ML. Estrogens and progestins: background and history, trends in use, and guidelines and regimens approved by the US Food and Drug Administration. Am J Med 2005; 118: (Suppl 12B): 64–73.
-
- Woodruff JD, Pickar JH. Incidence of endometrial hyperplasia in postmenopausal women taking conjugated estrogens (Premarin) with medroxyprogesterone acetate or conjugated estrogens alone. Am J Obstet Gynecol 1994; 170:1213–1223.
-
- Osteoporosis. National Institutes of Health Consensus Development Conference Statement. Natl Inst Health Consens Dev Conf Consens Statement. 1984;5(3):6.
-
- Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA 2002; 288:321–333.
-
- Paciuc J. Hormone therapy in menopause. Adv Exp Med Biol 2020; 1242:89–120.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Research Materials
Miscellaneous