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. 2023 Mar 13;38(3):267-272.
doi: 10.1515/dmpt-2022-0180. eCollection 2023 Sep 1.

Lack of exposure to pharmacogenomics education among the health care providing students in the West Bank of Palestine

Yazun Jarrar  1 , Rami Musleh  2 , Anas Hamdan  3 , Mustafa Ghanim  3 , Malik Alqub  4 , Sara Abudahab  5
Affiliations

Lack of exposure to pharmacogenomics education among the health care providing students in the West Bank of Palestine

Yazun Jarrar et al. Drug Metab Pers Ther. .

Abstract

Objectives: Evaluating the knowledge in pharmacogenomics (PGx) is the first step toward the implementation of PGx testing in clinical practice. This survey aimed to evaluate the knowledge of PGx testing among healthcare providing students at the top-ranked university in the West Bank of Palestine.

Methods: First an online questionnaire consisting of 30 questions regarding the demographic, knowledge, and attitude toward pharmacogenomics testing was structured and validated. Then the questionnaire was distributed to 1,000 current students from different fields.

Results: 696 responses was received. The results showed that almost half of the participants (n=355, 51.1%) have never took any courses about PGx during their university training. Only 81 (11.7%) of the students who took the PGx course stated that it helped them understanding how genetic variations affect drug response. The majority of the students were uncertain (n=352, 50.6%) or disagreed (n=143, 20.6%) that the lectures during university education described the effects of genetic variants on drug response. Although most of the students (70-80%) answered that genetic variants can indeed affect the drug's response, only 162 students (23.3%) responded that VKORC1 and CYP2C9 genotypes influence the response to warfarin. In addition, only 94 (13.5%) students were aware that many medicine labels include clinical information about PGx testing provided by the FDA.

Conclusions: It is concluded from the results of this survey that there is a lack of exposure to PGx education associated with poor knowledge of PGx testing among the healthcare providing students in the West Bank of Palestine. It is recommended to include and improve the lectures and courses regarding PGx as this will have a major impact on precision medicine.

Keywords: West Bank of Palestine; education; knowledge; pharmacogenomics (PGx).

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